Bavituximab Activates CD8+TILs in a 3D Ex Vivo System of Lung Cancer Patients Derived Tumors With Negative PD-L1 Expression

被引：0

作者：

Altiok, Soner ^{[1
]}

Valera, Melanie Mediavilla ^{[1
]}

Kreahling, Jenny ^{[1
]}

Kallinteris, Nikoletta L. ^{[2
]}

Noyes, David ^{[3
]}

Razabdouski, Tiffany N. ^{[3
]}

Shan, Joseph ^{[2
]}

Hutchins, Jeff ^{[2
]}

Menander, Kerstin ^{[2
]}

Antonia, Scott J. ^{[3
]}

机构：

[1] Nilogen Oncosyst, Tampa, FL USA

[2] Peregrine Pharmaceut, Clin, Tustin, CA USA

[3] Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33682 USA

来源：

JOURNAL OF THORACIC ONCOLOGY | 2015年 / 10卷 / 09期

关键词：

Tumor microenvironment immunomodulation; 3D tumor microspheres; Chimeric monoclonal antibody-targeted therapy; Cytokine and immne function genes profiling-TILs activation;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

MINI14.07

引用

页码：S312 / S313

页数：2

共 50 条

[31] Clinical Relevance of PD-L1 Expression and CD8+T Cells' Infiltration in Patients With Lung Invasive Mucinous Adenocarcinoma
Xu, Xiaoling
Li, Na
Wang, Ding
Chen, Wei
Fan, Yun
FRONTIERS IN ONCOLOGY, 2021, 11
[32] Intratumoral Programmed Cell Death-Ligand 1 (PD-L1) and Intratumoral CD8+ T Cell Expression in Lung Cancer
Jin, Yasuto
Matsubara, Osamu
Yamanaka, Kazuki
Mark, Eugene
MODERN PATHOLOGY, 2017, 30 : 481A - 481A
[33] Intratumoral programmed cell death-ligand 1 (PD-L1) and Intratumoral CD8+T cell Expression in Lung Cancer
Jin, Yasuto
Yamauchi, Shuta
Shimada, Hiroyuki
Matsubara, Osamu
CANCER SCIENCE, 2018, 109 : 1099 - 1099
[34] Intratumoral Programmed Cell Death-Ligand 1 (PD-L1) and Intratumoral CD8+ T Cell Expression in Lung Cancer
Jin, Yasuto
Matsubara, Osamu
Yamanaka, Kazuki
Mark, Eugene
LABORATORY INVESTIGATION, 2017, 97 : 481A - 481A
[35] Prognostic significance of PD-L1 expression and CD8+ TILs density for disease-free survival in surgically resected lung squamous cell carcinoma: a retrospective study
Cheng, Xiaomin
Wang, Lei
Zhang, Zhemin
JOURNAL OF THORACIC DISEASE, 2022, 14 (06) : 2224 - 2234
[36] The effect of neoadjuvant therapy on PD-L1 expression and CD8+lymphocyte density in non-small cell lung cancer
Zens, Philipp
Bello, Corina
Scherz, Amina
von Gunten, Michael
Ochsenbein, Adrian
Schmid, Ralph A.
Berezowska, Sabina
MODERN PATHOLOGY, 2022, 35 (12) : 1848 - 1859
[37] Association of tumor and stroma PD-1, PD-L1, CD3, CD4 and CD8 expression with response to nivolumab treatment in NSCLC patients
Sahba, S.
Niemeijer, A-L.
De langen, J.
Thunnissen, E.
ANNALS OF ONCOLOGY, 2017, 28
[38] PD-L1 expression level and CD8+/FoxP3+ T cell ratio in breast cancer and prognosis
Hattori, Masaya
Khramtsova, Galina
Sveen, Lise
Yoshimatsu, Toshio
Huo, Dezheng
Olopade, Olufunmilayo I.
CANCER RESEARCH, 2019, 79 (13)
[39] Expression of intratumoral PD-L1 and intratumoral CD4+T cell, CD8+T cell, and FOXP3+T cell in lung cancer
Shimada, Hiroyuki
Yamauchi, Shuta
Jin, Yasuto
CANCER SCIENCE, 2018, 109 : 1410 - 1410
[40] Clinical Significance of PD-L1 Expression and CD8-Positive Tumor-Infiltrating Lymphocytes in Patients with Cavitary Lung Adenocarcinoma
Liu, Jiangyong
Gu, Mingming
Xue, Yang
Wang, Qiong
Ren, Yong
Huang, Wencai
ONCOLOGIE, 2021, 23 (03) : 439 - 452

← 1 2 3 4 5 →