Chemical Modification of Oligonucleotides for Therapeutic, Bioanalytical and other Applications

被引:91
|
作者
Bell, Neil M. [1 ]
Micklefield, Jason [1 ]
机构
[1] Univ Manchester, Sch Chem, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
关键词
antisense agents; conjugation; nucleic acids; oligonucleotides; RNAi; PEPTIDE NUCLEIC-ACIDS; RNA-INTERFERENCE; ANTISENSE OLIGONUCLEOTIDES; ANTIVIRAL ACTIVITY; DNA; INHIBITION; EXPRESSION; PNA; DESIGN; MICE;
D O I
10.1002/cbic.200900341
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:2691 / 2703
页数:13
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