Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles

被引：11
|
作者：
Schmidt, Elena Yu [1 ]
Ivanova, Elena V. [1 ]
Semenova, Nadezhda V. [1 ]
Tatarinova, Inna V. [1 ]
Ushakov, Igor A. [1 ]
Trofimov, Boris A. [1 ]
机构：
[1] Russian Acad Sci, Siberian Branch, AE Favorsky Irkutsk Inst Chem, Irkutsk 664033, Russia
来源：
MENDELEEV COMMUNICATIONS | 2015年 / 25卷 / 02期
关键词：
BUILDING-BLOCKS; ARYLACETYLENES; LIGANDS; STYRENE;
D O I：
10.1016/j.mencom.2015.03.018
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The sequential reaction of ketones with phenylacetylene in the presence of KOH/DMSO system followed by the treatment of the reaction mixture with HCl and monosubstituted hydrazines leads to pyrazolines and pyrazoles in up to 87% total yield.
引用
收藏
页码：131 / 132
页数：2
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