Pattern and incidence of cancer in Northern Saudi Arabia

Objective: To study the pattern and incidence of cancer in the Al-Jouf region of Saudi Arabia. Methods: The record of all confirmed cancer cases were retrieved and studied from the files of the Histopathology and Cytology Department, Prince Abdulrahman Al-Sudairy Central Hospital, Al-Jouf, Kingdom of Saudi Arabia (KSA) during the period 1994 to 2001. The major types of cancer were ranked in order of relative frequency. The crude incidence rate and age standardized rate were then calculated. Results: The age standardized rate in Al-Jouf was 38.5 per 100,000, a figure lower than the Saudi Arabian national average of 71.7 per 100,000 and lower than the lowest published international figure of 39.6 from Gambia. The most common cancers in the whole population irrespective of sex were carcinoma of the breast, lymphoma and leukemia combined and colorectal cancer. The most common cancers in females in Al Jouf were those of the breast, thyroid, and lymphomas and leukemia combined. Comparative findings for males were lymphomas and leukemias combined, colorectal and skin cancers. Conclusion: The incidence of cancer in Al Jouf region appears to be the lowest incidence published to date. The over all pattern of cancer is however similar to the findings in other regions of KSA. Carcinoma of breast, lymphomas and leukemias, and colorectal cancers are the leading cancers in the region.