Extended-release trazodone in the treatment of major depressive disorder

被引：0
|
作者：
Karamustafalioglu, Oguz [1 ]
Dilbaz, Nesrin [2 ]
Caykoylu, Ali [3 ]
Alkin, Tunc [4 ]
Gonul, Ali Saffet [5 ]
Atmaca, Murad [6 ]
机构：
[1] Adli Tip Kurumu, Istanbul, Turkey
[2] Uskudar Univ, ITBF Psikol Bolumu, Istanbul, Turkey
[3] Ankara Yildirim Beyazit Univ, Psikiyatri & Davranissal Norobilim Uygulama & Ara, Ankara, Turkey
[4] Dokuz Eylul Univ, Tip Fak, Psikiyatri ABD, Izmir, Turkey
[5] Ege Univ, Tip Fak, Psikiyatri ABD, Izmir, Turkey
[6] Firat Univ, Tip Fak, Psikiyatri ABD, Elazig, Turkey
来源：
ANADOLU PSIKIYATRI DERGISI-ANATOLIAN JOURNAL OF PSYCHIATRY | 2019年 / 20卷 / 05期
关键词：
major depressive disorder; extended-release trazodone (single dose of TzCOAD per day); immediate-release trazodone (three doses of TzIR per day); PROLONGED-RELEASE; TOLERABILITY; EFFICACY;
D O I：
10.5455/apd.302644467
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Major depressive disorder is a common psychiatric disorder. The aim of the treatment is to improve daily functions with remissions in symptoms, and antidepressants are the first-line treatments for a major depressive episode (moderate-severe depressive episode). In this paper, the pharmacological properties, clinical efficacy and safety of extended-release trazodone (TzCOAD) are studied. Expert opinion: A single daily dose of TzCOAD may provide similar efficacy and increased tolerability to immediate-release trazodone (TzIR) and other antidepressants.
引用
收藏
页码：453 / 459
页数：7
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