Enhanced aldol reaction using an aldolase I antibody immobilized in 3D mesoporous silica foam

被引:20
|
作者
Seelan, Sindhu
Sinha, Anil K.
Kato, Katsuya
Yokogawa, Yoshiyuki
机构
[1] Natl Inst Adv Ind Sci & Technol, Moriyama Ku, Nagoya, Aichi 4638560, Japan
[2] Toyota Cent Res & Dev Labs Inc, Nagakute, Aichi 4801192, Japan
关键词
D O I
10.1002/adma.200502644
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
3D foamlike mesoporous silica with ca. 16 nin pore size (see figure) has been used to immobilize aldolase antibody 84G3. This immobilization results in significantly accelerated and stable a1dol reactions at similar selectivities (> 98 % ee) compared to those of the free antibody.
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页码:3001 / +
页数:5
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