A phase 1/2 study of Ad.p53 DC vaccine with indoximod immunotherapy in metastatic breast cancer

被引：1
|
作者：
Soliman, Hatem H. [1 ]
Minton, Susan E. [1 ]
Ismail-Khan, Roohi [1 ]
Han, Hyo S. [1 ]
Vahanian, Nicholas N. [2 ]
Link, Charles J. [2 ]
Kennedy, Gene [2 ]
Streicher, Howard [3 ]
Sullivan, Daniel [1 ]
Antonia, Scott J. [1 ]
机构：
[1] H Lee Moffitt Canc Ctr & Res Inst, Temple, TX USA
[2] NewLink Genet Inc, Ames, IA USA
[3] Natl Canc Inst, Bethesda, MD USA
来源：
CANCER RESEARCH | 2015年 / 75卷
关键词：
D O I：
10.1158/1538-7445.SABCS14-P2-15-04
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P2-15-04
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Phase II study of talazoparib, a PARP inhibitor, in somatic BRCA1/2 mutant metastatic breast cancer
    Vidula, Neelima
    Horick, Nora
    Basile, Erin
    Blouch, Erica
    Ellisen, Leif W.
    Rugo, Hope S.
    Bardia, Aditya
    CANCER RESEARCH, 2021, 81 (04)
  • [42] Phase II Study of S-1 in Combination with Trastuzumab for HER2-positive Metastatic Breast Cancer
    Takashima, Tsutomu
    Nakayama, Takahiro
    Yoshidome, Katsuhide
    Kawajiri, Hidemi
    Kamigaki, Shunji
    Tsurutani, Junji
    Arai, Takashi
    Ito, Toshikazu
    Komoike, Yoshihumi
    Doi, Takako
    Masuda, Norikazu
    Miyauchi, Keisuke
    Miyoshi, Yasuo
    Sakamoto, Junichi
    Morita, Satoshi
    Taguchi, Tetsuya
    ANTICANCER RESEARCH, 2014, 34 (07) : 3583 - 3588
  • [43] IMMUNOHISTOCHEMICAL STUDY OF P53 AND C-ERBB-2 IN BREAST-CANCER
    CASTIGLIONI, T
    ELSNER, B
    CURUTCHET, HP
    MONTESINOS, M
    DEBONIS, D
    MEDICINA-BUENOS AIRES, 1995, 55 (05) : 415 - 420
  • [44] Abemaciclib in combination with therapies for patients with metastatic breast cancer: a phase 1b study
    Tolaney, Sara M.
    Jhaveri, Komal
    Helsten, Teresa
    Puhalla, Shannon L.
    Conlin, Alison
    Dees, E. Claire
    Beeram, Muralidhar
    Chapman, Sonya C.
    Lithio, Andrew
    Litchfield, Lacey M.
    Goetz, Matthew P.
    FRONTIERS IN ONCOLOGY, 2025, 15
  • [45] Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer: A single-arm phase II study
    Vermeij, Renee
    Leffers, Ninke
    Hoogeboom, Baukje-Nynke
    Hamming, Ineke L. E.
    Wolf, Rinze
    Reyners, Anna K. L.
    Molmans, Barbara H. W.
    Hollema, Harry
    Bart, Joost
    Drijfhout, Jan W.
    Oostendorp, Jaap
    van der Zee, Ate G. J.
    Melief, Cornelis J.
    van der Burg, Sjoerd H.
    Daemen, Toos
    Nijman, Hans W.
    INTERNATIONAL JOURNAL OF CANCER, 2012, 131 (05) : E670 - E680
  • [46] A phase I study of a p53MVA vaccine in combination with gemcitabine (GEM) in recurrent ovarian cancer (OC).
    Cristea, Mihaela C.
    Hardwick, Nicola
    Frankel, Paul Henry
    Morgan, Robert
    Leong, Lucille A.
    Diamond, Don J.
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [47] Results of a Phase I/IIa Trial of Combination Whole-Cell Targeted Immunotherapy Vaccine and Checkpoint Inhibitor in Treatment of Metastatic/Recurrent Breast Cancer
    Bohan, P. Kemp
    Chick, R. C.
    Clifton, G. T.
    Vreeland, T. J.
    Hale, D. F.
    Sunkari, V.
    Lacher, M.
    Wiseman, C. L.
    Peoples, G. E.
    Williams, W. V.
    ANNALS OF SURGICAL ONCOLOGY, 2020, 27 (SUPPL 1) : S130 - S130
  • [48] Repurposing ibrutinib for chemo-immunotherapy in a phase 1b study of ibrutinib with indoximod plus metronomic cyclophosphamide and etoposide for patients with childhood brain cancer.
    Johnson, Theodore S.
    Pacholczyk, Rafal
    Satpathy, Sarthak
    Berrong, Zuzana
    Creager, Julianne
    Huang, Chenbin
    Kennedy, Eugene Paul
    Ring, Eric K.
    Sadek, Ramses F.
    Thomas, Beena E.
    Bhasin, Manoj K.
    Munn, David H.
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [49] Immunotherapy with GVAX® vaccine for prostate cancer improves predicted survival in metastatic hormone refractory prostate cancer:: Results from two phase 2 studies
    Corman, JM
    Small, E
    Smith, D
    Centeno, A
    Gittelman, M
    Steidle, C
    Sacks, N
    Simons, JW
    JOURNAL OF UROLOGY, 2006, 175 (04): : 315 - 315
  • [50] A phase I study of the combination of docetaxel (D) and adriamicin (AD) in first line CT treatment of metastatic breast cancer (MBC)
    Dieras, V
    Gruia, G
    Pouillart, P
    Cvitkovic, E
    Gentin, M
    Azli, N
    Riva, A
    Misset, JL
    EUROPEAN JOURNAL OF CANCER, 1995, 31A : 935 - 935
12345