Hyperspherical von mises-fisher mixture (HvMF) modelling of high angular resolution diffusion MRI

被引:0
|
作者
Bhalerao, Abhir [1 ]
Westin, Carl-Fredrik [2 ]
机构
[1] Univ Warwick, Dept Comp Sci, Coventry CV4 7AL, W Midlands, England
[2] Harvard Med Sch, Brigham & Womens Hosp, Lab Math Imaging, Boston, MA 02115 USA
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中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
A mapping of unit vectors onto a 5D hypersphere is used to model and partition ODFs from HARDI data. This mapping has a number of useful and interesting properties and we make a link to interpretation of the second order spherical harmonic decompositions of HARDI data. The paper presents the working theory and experiments of using a von Mises-Fisher mixture model for directional samples. The MLE of the second moment of the HvMF pdf can also be related to fractional anisotropy. We perform error analysis of the estimation scheme in single and multi-fibre regions and then show how a penalised-likelihood model selection method can be employed to differentiate single and multiple fibre regions.
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页码:236 / +
页数:2
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