Concomitant inhibition of Bcl-xL and Mcl-1 expression by RNA interference as a novel strategy for the treatment of ovarian carcinomas

被引：0
|
作者：
Denoyelle, C. [1 ]
Brotin, E. [1 ]
Duval, R. [1 ]
Simonin, K. [1 ]
Meryet-Figuiere, M. [1 ]
N'Diaye, M. [1 ]
Louis, M. H. [1 ]
Dutoit, S. [1 ]
Gauduchon, P. [1 ]
Poulain, L. [1 ]
机构：
[1] Ctr Francois Baclesse, F-14021 Caen, France
来源：
EJC SUPPLEMENTS | 2008年 / 6卷 / 09期
关键词：
D O I：
10.1016/S1359-6349(08)71490-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：81 / 82
页数：2
相关论文
共 50 条
  • [41] Functional apoptosis profiling identifies MCL-1 and BCL-xL as prognostic markers and therapeutic targets in advanced thymomas and thymic carcinomas
    Mueller, Denise
    Mazzeo, Paolo
    Koch, Raphael
    Boesherz, Mark-Sebastian
    Welter, Stefan
    Von Hammerstein-Equord, Alexander
    Hinterthaner, Marc
    Cordes, Lucia
    Belharazem, Djeda
    Marx, Alexander
    Stroebel, Philipp
    Kueffer, Stefan
    BMC MEDICINE, 2021, 19 (01)
  • [42] Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells
    Siti Fairus Abdul Rahman
    Azali Azlan
    Kwok-Wai Lo
    Ghows Azzam
    Nethia Mohana-Kumaran
    Discover Oncology, 13
  • [43] Functional apoptosis profiling identifies MCL-1 and BCL-xL as prognostic markers and therapeutic targets in advanced thymomas and thymic carcinomas
    Denise Müller
    Paolo Mazzeo
    Raphael Koch
    Mark-Sebastian Bösherz
    Stefan Welter
    Alexander von Hammerstein-Equord
    Marc Hinterthaner
    Lucia Cordes
    Djeda Belharazem
    Alexander Marx
    Philipp Ströbel
    Stefan Küffer
    BMC Medicine, 19
  • [44] Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins
    Zhuang, Liqing
    Scolyer, Richard A.
    Murali, Rajmohan
    McCarthy, Stanley W.
    Zhang, Xu Dong
    Thompson, John F.
    Hersey, Peter
    MODERN PATHOLOGY, 2010, 23 (01) : 45 - 53
  • [45] BCL-xL/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cells
    Perri, Mariarita
    Yap, Jeremy L.
    Yu, Jianshi
    Cione, Erika
    Fletcher, Steven
    Kane, Maureen A.
    EXPERIMENTAL CELL RESEARCH, 2014, 327 (02) : 183 - 191
  • [46] BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL
    Greaves, Georgia
    Milani, Mateus
    Butterworth, Michael
    Carter, Rachel J.
    Byrne, Dominic P.
    Eyers, Patrick A.
    Luo, Xu
    Cohen, Gerald M.
    Varadarajan, Shankar
    CELL DEATH AND DIFFERENTIATION, 2019, 26 (06): : 1037 - 1047
  • [47] Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells
    Rahman, Siti Fairus Abdul
    Azlan, Azali
    Lo, Kwok-Wai
    Azzam, Ghows
    Mohana-Kumaran, Nethia
    DISCOVER ONCOLOGY, 2022, 13 (01)
  • [48] BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL
    Georgia Greaves
    Mateus Milani
    Michael Butterworth
    Rachel J. Carter
    Dominic P. Byrne
    Patrick A. Eyers
    Xu Luo
    Gerald M. Cohen
    Shankar Varadarajan
    Cell Death & Differentiation, 2019, 26 : 1037 - 1047
  • [49] Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells
    Morales, Alejo A.
    Kurtoglu, Metin
    Matulis, Shannon M.
    Liu, Jiangxia
    Siefker, David
    Gutman, Delia M.
    Kaufman, Jonathan L.
    Lee, Kelvin P.
    Lonial, Sagar
    Boise, Lawrence H.
    BLOOD, 2011, 118 (05) : 1329 - 1339
  • [50] Mcl-1 and Bcl-xL Cooperatively Maintain Integrity of Hepatocytes in Developing and Adult Murine Liver
    Hikita, Hayato
    Takehara, Tetsuo
    Shimizu, Satoshi
    Kodama, Takahiro
    Li, Wei
    Miyagi, Takuya
    Hosui, Atsushi
    Ishida, Hisashi
    Ohkawa, Kazuyoshi
    Kanto, Tatsuya
    Hiramatsu, Naoki
    Yin, Xiao-Ming
    Hennighausen, Lothar
    Tatsumi, Tomohide
    Hayashi, Norio
    HEPATOLOGY, 2009, 50 (04) : 1217 - 1226
12345