Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome

被引：7

作者：

Oh, Mi Mi ^{[1
]}

Ham, Byeong Kuk ^{[1
]}

Kang, Seok Ho ^{[1
]}

Bae, Jae Hyun ^{[1
]}

Kim, Je Jong ^{[1
]}

Yoo, Ki Hwan ^{[2
]}

Yoon, Duck Ki ^{[1
]}

Moon, Du Geon ^{[1
]}

机构：

[1] Univ Korea Hosp, Dept Urol, Seoul 152703, South Korea

[2] Univ Korea Hosp, Dept Pediat, Seoul 152703, South Korea

来源：

UROLOGICAL RESEARCH | 2011年 / 39卷 / 05期

关键词：

Lesch-Nyhan syndrome; Urine alkalinization; Stones; ACID; DISSOLUTION; MANAGEMENT;

D O I：

10.1007/s00240-011-0364-z

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Lesch-Nyhan syndrome is a rare sex-linked disorder of purine metabolism that is caused by a mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene which causes marked hyperuricemia and hyperuricosuria, with signs of gouty arthritis and uric acid stone disease in early childhood. We report a case of renal pelvis calculi which was dissolved within 10 days of urine alkalinization and hydration.

引用

页码：417 / 419

页数：3

共 50 条

[21] RENAL ULTRASONOGRAPHIC APPEARANCES AT PRESENTATION IN AN INFANT WITH LESCH-NYHAN SYNDROME
LUDMAN, CN
DICKSMIREAUX, C
SAUNDERS, AJ
BRITISH JOURNAL OF RADIOLOGY, 1992, 65 (776): : 724 - 725
[22] Maximizing hypoxanthine levels with allopurinol to prevent renal stones in Lesch-Nyhan disease
Barea, Jaime J.
Nyhan, William L.
MOLECULAR GENETICS AND METABOLISM, 2015, 114 (03) : 371 - 371
[23] HYPOXANTHINE AND TETRAHYDROBIOPTERIN TREATMENT OF A PATIENT WITH FEATURES OF THE LESCH-NYHAN SYNDROME
MANZKE, H
GUSTMANN, H
KOKE, HG
NYHAN, WL
PEDIATRIC RESEARCH, 1985, 19 (07) : 763 - 763
[24] Botulinum toxin as a novel treatment for self mutilation in Lesch-Nyhan syndrome
Payne, MS
Nadell, JM
Tilton, AH
ANNALS OF NEUROLOGY, 2002, 52 (03) : S157 - S157
[25] PROBLEMS IN THE BEHAVIORAL TREATMENT OF SELF-INJURY IN THE LESCH-NYHAN SYNDROME
GILBERT, S
SPELLACY, E
WATTS, RWE
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 1979, 21 (06): : 795 - 800
[26] ACUTE RENAL-FAILURE DURING ADENINE THERAPY IN LESCH-NYHAN SYNDROME
CECCARELLI, M
CIOMPI, ML
TADDEUCCI, G
PASERO, G
ISRAEL JOURNAL OF MEDICAL SCIENCES, 1973, 9 (08): : 1087 - 1087
[27] HYPERURICEMIA ASSOCIATED WITH 18Q DELETION - ATYPICAL LESCH-NYHAN SYNDROME
LASZLO, A
OSZTOVICS, M
DALLMANN, L
MATTYUS, A
ANNALES DE GENETIQUE, 1981, 24 (01): : 17 - 20
[28] MEMBRANE-ASSOCIATED HPRTASE ACTIVITY IN HYPERURICEMIC AND LESCH-NYHAN SYNDROME CELLS
YIP, LC
XU, YL
BALIS, ME
CHINESE MEDICAL JOURNAL, 1986, 99 (11) : 927 - 930
[29] Botulinum toxin: Treatment of self-mutilation in patients with Lesch-Nyhan syndrome
Gutierrez, Cristiam
Pellene, Alejandro
Micheli, Federico
CLINICAL NEUROPHARMACOLOGY, 2008, 31 (03) : 180 - 183
[30] Botulinum toxin as a novel treatment for self-mutilation in Lesch-Nyhan syndrome
Dabrowski, E
Smathers, SA
Ralstrom, CS
Nigro, MA
Leleszi, JP
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2005, 47 (09): : 636 - 639

← 1 2 3 4 5 →