ALZHEIMER'S DISEASE: MECHANISMS OF TAU AND AMYLOID BETA-INDUCED EXCITOTOXICITY

被引：0
|
作者：
Lin, Xiaotong [1 ]
Yan, Tingting [1 ]
机构：
[1] Harbin Inst Technol, Dept Bioengn, Weihai 264209, Shandong, Peoples R China
来源：
PROCEEDINGS OF THE 2016 INTERNATIONAL CONFERENCE ON BIOTECHNOLOGY & MEDICAL SCIENCE | 2017年
基金：
中国国家自然科学基金;
关键词：
NEURODEGENERATIVE DISEASES; GLUTAMATE; RECEPTORS; PROTEINS;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Excitotoxicity is associated with various neurodegenerative diseases, among which Alzheimer's disease (AD) and Parkinson disease (PD) are the typical diseases. AD is a representative degenerative disease with clinical characteristics of senile plaques (SPs), neurofibrillary tangles (NFTs) and neuronal loss. Excitotoxicity has been considered as a mechanism of AD pathogenesis, which may induced by excessive accumulation of glutamate.
引用
收藏
页码：386 / 391
页数：6
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