Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\

被引:0
|
作者
Du, YH
Lin, L
Miller, SB
Alp, NJ
Channon, KM
Galligan, JJ
Fink, GD
Chen, AF
机构
[1] Michigan State Univ, E Lansing, MI 48824 USA
[2] Univ Oxford, Oxford OX1 2JD, England
关键词
D O I
暂无
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
引用
收藏
页码:817 / 817
页数:1
相关论文
共 36 条
  • [21] Activation of Peroxisome Proliferatior-Activated Receptor-delta Prevents Endothelial Dysfunction in Mouse Model of GTP-Cyclohydrolase I Deficiency
    d'Uscio, Livius V.
    Santhanam, Anantha V.
    Smith, Leslie A.
    Katusic, Zvonimir S.
    CIRCULATION, 2010, 122 (21)
  • [22] GTP cyclohydrolase I prevents diabetic-impaired endothelial progenitor cells and wound healing by suppressing oxidative stress/thrombospondin-1
    Tie, Lu
    Chen, Lu-Yuan
    Chen, Dan-Dan
    Xie, He-Hui
    Channon, Keith M.
    Chen, Alex F.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2014, 306 (10): : E1120 - E1131
  • [23] Endothelial-targeted Overexpression of Heat Shock Protein 27 Ameliorates Rapid Blood Brain Barrier Impairment and Improves Long Term Outcomes After Ischemia and Reperfusion
    Shi, Yejie
    Jiang, Xiaoyan
    Zhang, Lili
    Pu, Hongjian
    Zhang, Wenting
    Gao, Yanqin
    Hu, Xiaoming
    Leak, Rehana K.
    Keep, Richard F.
    Bennett, Michael V.
    Chen, Jun
    STROKE, 2017, 48
  • [24] Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
    Alp, NJ
    Mussa, S
    Cai, SJ
    Goh, N
    Jefferson, A
    Channon, KM
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (05) : A82 - A82
  • [25] In vivo PPARα activation reduces blood pressure and NADPH oxidase/superoxide-induced endothelial dysfunction in mineralocorticoid hypertension
    Li, LX
    Yang, XQ
    DeMarco, AA
    Fink, GD
    Chen, AF
    HYPERTENSION, 2004, 44 (04) : 535 - 535
  • [26] Endothelial function and risk of hypertension and blood pressure progression: the prospective investigation of the vasculature in Uppsala seniors
    Lytsy, Per
    Lind, Lars
    Sundstrom, Johan
    JOURNAL OF HYPERTENSION, 2013, 31 (05) : 936 - 939
  • [27] Gene transfer of human GTP cyclohydrolase I restores arterial tetrahydrobiopterin level and endothelial dysfunction from ET-1 induced superoxide in low renin hypertension
    Chen, AF
    Zheng, JS
    Fink, GD
    Hesslinger, C
    Kapatos, G
    Kovesdi, I
    CIRCULATION, 2003, 108 (17) : 68 - 68
  • [28] Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice
    Adlam, D.
    Bendall, J. K.
    De Bono, J. P.
    Alp, N. J.
    Khoo, J.
    Nicoli, T.
    Yokoyama, M.
    Kawashima, S.
    Channon, K. M.
    EXPERIMENTAL PHYSIOLOGY, 2007, 92 (01) : 119 - 126
  • [29] Effects of low-fat dairy intake on blood pressure and endothelial function in subjects with pre-hypertension or stage I hypertension
    Maki, Kevin
    Rains, Tia
    Schild, Arianne
    Dicklin, Mary
    Lawless, Andrea
    Kelley, Kathleen
    Park, Keigan
    FASEB JOURNAL, 2013, 27
  • [30] Reducing Visit-To-Visit Variability in Systolic Blood Pressure for Improving the Progression of Carotid Atherosclerosis and Endothelial Dysfunction in Patients with Hypertension Management
    Song, Hongbin
    Liu, Zhendong
    Zhao, Yingxin
    Ye, Lin
    Lu, Fanghong
    Zhang, Hua
    Diao, Yutao
    Xu, Jianchao
    IRANIAN JOURNAL OF PUBLIC HEALTH, 2014, 43 (06) : 722 - 735