Metabolic abnormalities and body fat redistribution in HIV-1 infected patients:: the lipodystrophy syndrome

被引：34

作者：

Martínez, E ^{[1
]}

Gatell, JM ^{[1
]}

机构：

[1] Hosp Clin Barcelona, IDIBAPS, Infect Dis Unit, E-08036 Barcelona, Spain

来源：

CURRENT OPINION IN INFECTIOUS DISEASES | 1999年 / 12卷 / 01期

关键词：

D O I：

10.1097/00001432-199902000-00003

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A unique and unexpected syndrome consisting of metabolic abnormalities (hyperlipidaemia and insulin resistance) and body fat redistribution (central adiposity and peripheral fat wasting) has been reported with increasing frequency in HIV-1 infected patients, most of whom are receiving highly active antiretroviral therapies including HIV-I protease inhibitors. This article reviews the clinical and laboratory characteristics, the pathogenesis, and the management of this syndrome. Curr Opin Infect Dis 12:13-19. (C) 1999 Lippincott Williams & Wilkins.

引用

页码：13 / 19

页数：7

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