Metabolic abnormalities and body fat redistribution in HIV-1 infected patients:: the lipodystrophy syndrome

被引：34
|
作者：
Martínez, E [1 ]
Gatell, JM [1 ]
机构：
[1] Hosp Clin Barcelona, IDIBAPS, Infect Dis Unit, E-08036 Barcelona, Spain
来源：
CURRENT OPINION IN INFECTIOUS DISEASES | 1999年 / 12卷 / 01期
关键词：
D O I：
10.1097/00001432-199902000-00003
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
A unique and unexpected syndrome consisting of metabolic abnormalities (hyperlipidaemia and insulin resistance) and body fat redistribution (central adiposity and peripheral fat wasting) has been reported with increasing frequency in HIV-1 infected patients, most of whom are receiving highly active antiretroviral therapies including HIV-I protease inhibitors. This article reviews the clinical and laboratory characteristics, the pathogenesis, and the management of this syndrome. Curr Opin Infect Dis 12:13-19. (C) 1999 Lippincott Williams & Wilkins.
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收藏
页码：13 / 19
页数：7
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