X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations

被引：70

作者：

Kascakova, Slavka ^{[1
,2
]}

Giuliani, Alexandre ^{[1
,3
]}

Lacerda, Sara ^{[4
]}

Pallier, Agnes ^{[4
]}

Mercere, Pascal ^{[1
]}

Toth, Eva ^{[4
]}

Refregiers, Matthieu ^{[1
]}

机构：

[1] Synchrotron SOLEIL, F-91190 Gif Sur Yvette, France

[2] Univ Paris 11, UMR S1193, F-94800 Villejuif, France

[3] INRA, UAR1008, Caracterisat & Elaborat Prod Issus Agr, F-44316 Nantes, France

[4] CNRS, Ctr Biophys Mol, F-45071 Orleans 2, France

来源：

NANO RESEARCH | 2015年 / 8卷 / 07期

关键词：

photodynamic therapy; liponanoparticles; X-ray; deep tumour; photosensitizer; CONTRAST AGENTS; QUANTUM-DOT; LUMINESCENCE; HYPERICIN; COMPLEXES; CELLS; MRI;

D O I：

10.1007/s12274-015-0747-5

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We report lanthanide-based micelles integrating hypericin (Hyp) for X-ray-triggered photodynamic therapy (PDT). The lanthanide luminescence induced by X-ray irradiation excites the photosensitizer, which leads to the generation of singlet oxygen. This versatile approach can be extended to other photosensitizers or other types of liponanoparticles and can allow for magnetic resonance imaging (MRI) guidance.

引用

页码：2373 / 2379

页数：7

共 50 条

[21] Copper iodine cluster nanoparticles for tumor-targeted X-ray-induced photodynamic therapy
Xie, Wei
Chen, Junyun
Zhang, Yuxin
Zheng, Biyuan
Li, Xingshu
Huang, Jian-Dong
SCIENCE CHINA-MATERIALS, 2024, 67 (10) : 3358 - 3367
[22] Avenue to X-ray-induced photodynamic therapy of prostatic carcinoma with octahedral molybdenum cluster nanoparticles
Koncosova, Martina
Rumlova, Michaela
Mikyskova, Romana
Reinis, Milan
Zelenka, Jaroslav
Ruml, Tomas
Kirakci, Kaplan
Lang, Kamil
JOURNAL OF MATERIALS CHEMISTRY B, 2022, 10 (17) : 3303 - 3310
[23] Application of Mitochondrially Targeted Nanoconstructs to Neoadjuvant X-ray-Induced Photodynamic Therapy for Rectal Cancer
Deng, Wei
McKelvey, Kelly J.
Guller, Anna
Fayzullin, Alexey
Campbell, Jared M.
Clement, Sandhya
Habibalahi, Abbas
Wargocka, Zofia
Liang, Liuen
Shen, Chao
Howell, Viive Maarika
Engel, Alexander Frank
Goldys, Ewa M.
ACS CENTRAL SCIENCE, 2020, 6 (05) : 715 - 726
[24] Nanoscale Metal-Organic Layers for Deeply Penetrating X-ray-Induced Photodynamic Therapy
Lan, Guangxu
Ni, Kaiyuan
Xu, Ruoyu
Lu, Kuangda
Lin, Zekai
Chan, Christina
Lin, Wenbin
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 56 (40) : 12102 - 12106
[25] Erratum: Surface studies of solids using integral X-ray-induced photoemission yield
Stanislav Stoupin
Mikhail Zhernenkov
Bing Shi
Scientific Reports, 7
[26] DETERMINATION OF X-RAY-INDUCED DAMAGE TO THE MURINE COLON USING TISSUE COMPLIANCE MEASUREMENTS
MARTIN, SG
VOJNOVIC, B
MURRAY, JC
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1991, 59 (02) : 503 - 515
[27] In situ Monitoring of Synchrotron X-Ray-Induced Radiolysis Effects on Chromium Species Using X-Ray Absorption Spectroscopy
Men, S.
Anderson, A. J.
Mayanovic, R. A.
JOURNAL OF APPLIED SPECTROSCOPY, 2017, 84 (02) : 342 - 345
[28] In situ Monitoring of Synchrotron X-Ray-Induced Radiolysis Effects on Chromium Species Using X-Ray Absorption Spectroscopy
S. Men
A. J. Anderson
R. A. Mayanovic
Journal of Applied Spectroscopy, 2017, 84 : 342 - 345
[29] Hydrogen-Bonded Organic Framework Nanoscintillators for X-Ray-Induced Photodynamic Therapy in Hepatocellular Carcinoma
Gu, Lihui
Wu, Han
Li, Xu
Xu, Jiahao
Wang, Mingda
Li, Chao
Yao, Lanqing
Diao, Yongkang
Li, Yuchen
Chen, Fujie
Shen, Feng
Xiang, Huijing
Chen, Yu
Yang, Tian
ADVANCED MATERIALS, 2025,
[30] Terbium-Based AGuIX-Design Nanoparticle to Mediate X-ray-Induced Photodynamic Therapy
Daouk, Joel
Iltis, Mathilde
Dhaini, Batoul
Bechet, Denise
Arnoux, Philippe
Rocchi, Paul
Delconte, Alain
Habermeyer, Benoit
Lux, Francois
Frochot, Celine
Tillement, Olivier
Barberi-Heyob, Muriel
Schohn, Herve
PHARMACEUTICALS, 2021, 14 (05)

← 1 2 3 4 5 →