Direct synthesis of 2-substituted benzonitrilesviaalkylcyanation of arynes withN,N-disubstituted aminomalononitriles

被引：9
|
作者：
Bao, Wen [1 ,2 ]
Gao, Zhu-Peng [1 ,2 ]
Jin, Ping [1 ,2 ]
Xue, Cao-Gen [1 ,2 ]
Liang, Huan [1 ,2 ]
Lei, Ling-Sheng [1 ,2 ]
Xu, Xue-Tao [3 ]
Zhang, Kun [3 ]
Wang, Shao-Hua [1 ,2 ,3 ]
机构：
[1] Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[3] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 55期
基金：
中国国家自然科学基金;
关键词：
REGIOSPECIFIC SYNTHESIS; ALPHA-LITHIONITRILES; TANDEM ADDITION; INSERTION; CYANATION; REARRANGEMENT; CONSTRUCTION; DISCOVERY; BENZENES; ROUTE;
D O I：
10.1039/d0cc01591a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient alkylcyanation ofin situgenerated arynes byN,N-disubstituted aminomalononitriles is described, enabling the direct synthesis of 2-substituted benzonitriles.
引用
收藏
页码：7641 / 7644
页数：4
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