The Golgi: Keeping It Unapologetically Basic

被引：1

作者：

Ward, Nathan P. ^{[1
]}

DeNicola, Gina M. ^{[1
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Physiol, Tampa, FL 33612 USA

来源：

CANCER DISCOVERY | 2020年 / 10卷 / 06期

关键词：

PH; BIOLOGY; CANCER;

D O I：

10.1158/2159-8290.CD-20-0357

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Tumor cells maintain a reverse pH gradient relative to normal cells, conferring cell-intrinsic and cell-extrinsic benefits that sustain tumor growth. In this issue of Cancer Discovery, Galenkamp and colleagues reveal that NHE7 mediates acidification of the trans-Golgi network in pancreatic ductal adenocarcinoma, which is critical for the maintenance of cytosolic pH and consequently tumor growth.

引用

页码：768 / 770

页数：3

共 50 条

[41] RESPONSE OF THE GOLGI APPARATUS OF ABSORPTIVE CELLS OF THE DUODENUM, JEJUNUM, AND ILEUM IN RATS FED BASIC FOODSTUFFS
ADAMSTONE, FB
ANATOMICAL RECORD, 1957, 127 (02): : 393 - 394
[42] GOLGI APPARATUS AND GOLGI ZONE
HRSEL, I
BIOLOGIA PLANTARUM, 1967, 9 (03) : 157 - +
[43] Unapologetically Dramatic: Faye V. Harrison's Anthro-Performance Pedagogy
Maddox-Wingfield, Camee
TRANSFORMING ANTHROPOLOGY, 2020, 28 (02) : 120 - 121
[44] 'Keeping out, keeping in'
Wakefield, Richard
SEWANEE REVIEW, 2007, 115 (02) : 188 - 188
[45] Measures of Small Distributed Power Keeping Social Basic Operation Load under Extreme Disasters
Zhang Wenlei
Zeng Ming
Zhi Fei
Jiang Xinfan
Huang Lianggang
2012 ASIA-PACIFIC POWER AND ENERGY ENGINEERING CONFERENCE (APPEEC), 2012,
[46] BASIC DOCUMENTS ON UNITED-NATIONS AND RELATED PEACE-KEEPING FORCES - SIEKMANN,RCR
WOLONIECKI, JW
INTERNATIONAL AND COMPARATIVE LAW QUARTERLY, 1986, 35 : 481 - 482
[47] BASIC DOCUMENTS ON UNITED-NATIONS AND RELATED PEACE-KEEPING FORCES - SIEKMANN,RCR
MURPHY, JF
AMERICAN JOURNAL OF INTERNATIONAL LAW, 1986, 80 (04) : 1023 - 1024
[48] Selective Golgi α-mannosidase II inhibitors: N-alkyl substituted pyrrolidines with a basic functional group
Klunda, Tomas
Hricovini, Michal
Sestak, Sergej
Kona, Juraj
Polakova, Monika
NEW JOURNAL OF CHEMISTRY, 2021, 45 (24) : 10940 - 10951
[49] Keeping it real, keeping them interested and keeping it in their minds
Howley, Peter P.
JOURNAL OF STATISTICS EDUCATION, 2008, 16 (01):
[50] How Camillo Golgi became "the Golgi"
Mazzarello, Paolo
Garbarino, Carla
Calligaro, Alberto
FEBS LETTERS, 2009, 583 (23): : 3732 - 3737

← 1 2 3 4 5 →