Identification of the LIM protein Ajuba as a negative regulator of the Wnt signaling pathway

被引：0
|
作者：
Haraguchi, Keiko [1 ]
Ohsugi, Miho [1 ]
Abe, Yoshinori [1 ]
Akiyama, Tetsu [2 ]
Yamamoto, Tadashi [1 ]
机构：
[1] Univ Tokyo, Inst Med Sci, Dept Oncol, Tokyo 1138654, Japan
[2] Univ Tokyo, Inst Mol & Cellular Biosci, Lab Mol & Genet Informat, Tokyo 1138654, Japan
来源：
CELL STRUCTURE AND FUNCTION | 2004年 / 29卷
关键词：
cancer; signal transduction; cell proliferation;
D O I：
暂无
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：83 / 83
页数：1
相关论文
共 50 条
  • [21] Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling
    Cha, B.
    Kim, W.
    Kim, Y. K.
    Hwang, B. N.
    Park, S. Y.
    Yoon, J. W.
    Park, W. S.
    Cho, J. W.
    Bedford, M. T.
    Jho, E-h
    ONCOGENE, 2011, 30 (20) : 2379 - 2389
  • [22] Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM/ATR signaling pathway
    J L McConnell
    R J Gomez
    L R A McCorvey
    B K Law
    B E Wadzinski
    Oncogene, 2007, 26 : 6021 - 6030
  • [23] Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM/ATR signaling pathway
    McConnell, J. L.
    Gomez, R. J.
    McCorvey, L. R. A.
    Law, B. K.
    Wadzinski, B. E.
    ONCOGENE, 2007, 26 (41) : 6021 - 6030
  • [24] LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade
    I Tanaka
    H Osada
    M Fujii
    A Fukatsu
    T Hida
    Y Horio
    Y Kondo
    A Sato
    Y Hasegawa
    T Tsujimura
    Y Sekido
    Oncogene, 2015, 34 : 73 - 83
  • [25] Ajuba negatively regulates the Wnt signaling pathway by promoting GSK-3β-mediated phosphorylation of β-catenin
    K Haraguchi
    M Ohsugi
    Y Abe
    K Semba
    T Akiyama
    T Yamamoto
    Oncogene, 2008, 27 : 274 - 284
  • [26] Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin
    Gillis, William Q.
    Kirmizitas, Arif
    Iwasaki, Yasuno
    Ki, Dong-Hyuk
    Wyrick, Jonathan M.
    Thomsen, Gerald H.
    CELL COMMUNICATION AND SIGNALING, 2016, 14
  • [27] Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin
    William Q. Gillis
    Arif Kirmizitas
    Yasuno Iwasaki
    Dong-Hyuk Ki
    Jonathan M. Wyrick
    Gerald H. Thomsen
    Cell Communication and Signaling, 14
  • [28] LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade
    Tanaka, I.
    Osada, H.
    Fujii, M.
    Fukatsu, A.
    Hida, T.
    Horio, Y.
    Kondo, Y.
    Sato, A.
    Hasegawa, Y.
    Tsujimura, T.
    Sekido, Y.
    ONCOGENE, 2015, 34 (01) : 73 - 83
  • [29] Amer2 Protein Is a Novel Negative Regulator of Wnt/β-Catenin Signaling Involved in Neuroectodermal Patterning
    Pfister, Astrid S.
    Tanneberger, Kristina
    Schambony, Alexandra
    Behrens, Juergen
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (03) : 1734 - 1741
  • [30] The microRNA miR-8 is a conserved negative regulator of Wnt signaling
    Kennell, Jennifer A.
    Gerin, Isabelle
    MacDougald, Ormond A.
    Cadigan, Ken M.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (40) : 15417 - 15422
12345