Are RNAi and miRNA therapeutics truly dead?

被引：41
|
作者：
Conde, Joao [1 ,2 ]
Artzi, Natalie [1 ,3 ]
机构：
[1] MIT, Harvard Mit Div Hlth Sci & Technol, Inst Med Engn & Sci, Cambridge, MA 02139 USA
[2] Queen Mary Univ London, Sch Engn & Mat Sci, London, England
[3] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Anesthesiol, Boston, MA 02115 USA
来源：
TRENDS IN BIOTECHNOLOGY | 2015年 / 33卷 / 03期
关键词：
RNAi; delivery vehicle; pharmaceutical companies; nanotechnology; biomaterials; SIRNA DELIVERY; DESIGN; POTENT;
D O I：
10.1016/j.tibtech.2014.12.005
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Only a few years ago pharmaceutical companies were excited about the potential of RNA interference (RNAi). Now, financial volatility and subsequent dissolutions of in-house facilities by pharmaceutical companies have had media channels pronouncing that RNAi therapeutics are dead. However, advances in nanomedicine may now help the vast potential of RNAi therapeutics to be fulfilled.
引用
收藏
页码：141 / 144
页数：4
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