Oleanane-Type Triterpenoids from the Leaves and Twigs of Fatsia polycarpa

被引：18

作者：

Cheng, Shi-Yie ^{[1
]}

Wang, Chao-Min ^{[1
]}

Hsu, Yuan-Man ^{[2
]}

Huang, Tsurng-Juhn ^{[3
]}

Chou, Shen-Chieh ^{[3
]}

Lin, En-Hung ^{[1
]}

Chou, Chang-Hung ^{[1
,3
]}

机构：

[1] China Med Univ, Res Ctr Biodivers, Taichung 40402, Taiwan

[2] China Med Univ, Dept Biol Sci & Technol, Taichung 40402, Taiwan

[3] China Med Univ, Grad Inst Ecol & Evolutionary Biol, Taichung 40402, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 08期

关键词：

B VIRUS-REPLICATION; CELL-CULTURE ASSAY; FLOWER BUDS; JAPONICA; GLYCOSIDES; SAPONINS; CONSTITUENTS; DERIVATIVES; INFECTION;

D O I：

10.1021/np2002435

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Seven new oleanane-type triterpenoids (1-7), named fatsicarpains A-G, and the known compounds 3 alpha-hydroxyolean-11,13(18)-dien-28-oic acid (8) and 3 alpha-hydroxyolean-11-en-28,13 beta-olide (9) were isolated from the leaves and twigs of Fatsia polycarpa on the basis of bioassay-guided fractionation. The structures of compounds 1-7 were elucidated through spectroscopic analyses and single-crystal X-ray crystallography of 1, 8, and 9. Cytotoxicity against HepG2 2.2.15 and AGS cells and antihepatitis B virus (HBV) and antibacterial activities of 1-9 were also evaluated in vitro.

引用

页码：1744 / 1750

页数：7

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