Engineering cell shape and function through control of substrate adhesion

被引：0
|
作者：
Ingber, DE
机构：
来源：
POLYMER SURFACES AND INTERFACES: CHARACTERIZATION, MODIFICATION AND APPLICATION | 1997年
关键词：
extracellular matrix; cell culture; adhesion; microfabrication;
D O I：
暂无
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Recognition of the importance of cell adhesion for control of cell function has led to the development of novel techniques for fabricating bioactive substrates. Recent studies demonstrate that these culture substrata can modulate cell form, growth, and production of specialized products, independently of soluble serum components or defined growth factors. These new methods for engineering cell shape and function may be extremely useful for applications in biotechnology, such as drug screening, in vitro toxicology, genetic engineering, bioprocessing, and tissue engineering.
引用
收藏
页码：413 / 424
页数：12
相关论文
共 50 条
  • [31] How Substrate Properties Control Cell Adhesion. A Physical-Chemical Approach
    Carre, Alain
    Lacarriere, Valerie
    JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY, 2010, 24 (05) : 815 - 830
  • [32] Control of stem cell fate and function by engineering physical microenvironments
    Kshitiz
    Park, JinSeok
    Kim, Peter
    Helen, Wilda
    Engler, Adam J.
    Levchenko, Andre
    Kim, Deok-Ho
    INTEGRATIVE BIOLOGY, 2012, 4 (09) : 1008 - 1018
  • [33] The control of endothelial cell adhesion and migration by shear stress and matrix-substrate anchorage
    Teichmann, Juliane
    Morgenstern, Alexander
    Seebach, Jochen
    Schnittler, Hans-Joachim
    Werner, Carsten
    Pompe, Tilo
    BIOMATERIALS, 2012, 33 (07) : 1959 - 1969
  • [34] MOLECULAR/CELL ENGINEERING APPROACH TO AUTOCRINE LIGAND CONTROL OF CELL-FUNCTION
    LAUFFENBURGER, DA
    FORSTEN, KE
    WILL, B
    WILEY, HS
    ANNALS OF BIOMEDICAL ENGINEERING, 1995, 23 (03) : 208 - 215
  • [35] Selective adhesion method for nanocrystal shape control
    Alivisatos, AP
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 225 : U18 - U18
  • [36] A POSSIBLE FUNCTION IN CELL-SUBSTRATE ADHESION OF A METABOLIC PRODUCT OF L-M CELLS
    DANIEL, MR
    EXPERIMENTAL CELL RESEARCH, 1967, 46 (01) : 191 - &
  • [37] Adhesion in NK cell function
    Helander, TS
    Timonen, T
    SPECIFICITY, FUNCTION, AND DEVELOPMENT OF NK CELLS, 1998, 230 : 89 - 99
  • [38] Reciprocal regulation of endothelial substrate adhesion and barrier function
    Alexander, JS
    Zhu, YN
    Elrod, JW
    Alexander, B
    Coe, L
    Kalogeris, TJ
    Fuseler, J
    MICROCIRCULATION, 2001, 8 (06) : 389 - 401
  • [39] The Influence of Substrate Elasticity on Cell Adhesion Mechanisms
    Baster, Zbigniew
    Rajfur, Zenon
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 250A - 251A
  • [40] Engineering the Dynamics of Cell Adhesion Cues in Supramolecular Hydrogels for Facile Control over Cell Encapsulation and Behavior
    Diba, Mani
    Spaans, Sergio
    Hendrikse, Simone I. S.
    Bastings, Maartje M. C.
    Schotman, Maaike J. G.
    van Sprang, Johnick F.
    Wu, Dan Jing
    Hoeben, Freek J. M.
    Janssen, Henk M.
    Dankers, Patricia Y. W.
    ADVANCED MATERIALS, 2021, 33 (37)
12345