Non-random primary and secondary chromosomal abnormalities in human gastric cancers

被引：0
|
作者：
Yadav, M
Hopwood, VL
Multani, AS
Mansfield, PF
Takahashi, Y
McIntyre, BW
Udagawa, T
Pathak, S
机构：
[1] UNIV TEXAS, MD ANDERSON CANCER CTR, CELLULAR GENET LAB, DEPT CELL BIOL, HOUSTON, TX 77030 USA
[2] UNIV TEXAS, MD ANDERSON CANCER CTR, DEPT SURG ONCOL, HOUSTON, TX 77030 USA
[3] UNIV TEXAS, MD ANDERSON CANCER CTR, DEPT IMMUNOL, HOUSTON, TX 77030 USA
来源：
ANTICANCER RESEARCH | 1996年 / 16卷 / 4A期
关键词：
gastric cancer; cytogenetics; histopathology; karyotype; fluorescence in situ hybridization (FISH);
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
By using Giemsa-banding and fluorescence in situ hybridization techniques, we have been able to identify primary and secondary cytogenetic abnormalities in four gastric tumors at different stages of development. Structural and numerical abnormalities were present in all four gastric tumors in chromosomes 3, 7, 11, and X. Other abnormalities involving chromosomes 1, 5, 6, 8, 13, 15, 17, 18, 19 and 22 were observed, but only in three advanced gastric tumors, suggesting that these were secondary/tertiary genetic defects. Based on these results it was possible for us to decipher primary and secondary genetic abnormalities in these four gastric tumors.
引用
收藏
页码：1787 / 1795
页数：9
相关论文
共 50 条
  • [41] NON-RANDOM CHROMOSOMAL-ABERRATIONS IN A COMPLEX LEUKEMIC CLONE OF A BLOOMS SYNDROME PATIENT
    SHABTAI, F
    LEWINSKI, UH
    MEROZ, A
    KLAR, D
    DJALDETTI, M
    HALBRECHT, I
    [J]. HUMAN GENETICS, 1988, 80 (03) : 311 - 314
  • [42] NON-RANDOM CHROMOSOMAL CHANGES IN NON-HODGKIN MALIGNANT-LYMPHOMA - A REPORT ON 41 CASES
    FRAISSE, J
    JAUBERT, J
    LEPETIT, JC
    VASSELON, C
    GOURE, D
    BRIZARD, CP
    [J]. CLINICAL GENETICS, 1985, 27 (03) : 306 - 307
  • [43] Measuring the Efficiency of Purging by non-random Mating in Human Populations
    Laurent, Romain
    Gineau, Laure
    Utge, Jose
    Lafosse, Sophie
    Phoeung, Chan Leakhena
    Hegay, Tatyana
    Olaso, Robert
    Boland, Anne
    Deleuze, Jean-Francois
    Toupance, Bruno
    Heyer, Evelyne
    Leutenegger, Anne-Louise
    Chaix, Raphaelle
    [J]. MOLECULAR BIOLOGY AND EVOLUTION, 2024, 41 (06)
  • [44] NON-RANDOM KARYOTYPE VARIABILITY IN HUMAN CELL-LINES
    MAMAEVA, SE
    LITVINCHUK, LF
    PINAEV, GP
    [J]. DOKLADY AKADEMII NAUK SSSR, 1983, 270 (02): : 456 - &
  • [45] NON-RANDOM CHROMOSOME CHANGES IN HUMAN-MALIGNANT MELANOMA
    BALABAN, G
    HERLYN, M
    GUERRY, D
    NOWELL, P
    [J]. PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1983, 24 (MAR): : 10 - 10
  • [46] NON-RANDOM REPRESENTATION OF CHROMOSOME TYPES IN HUMAN TUMOR STEMLINES
    LEVAN, A
    [J]. HEREDITAS-GENETISKT ARKIV, 1966, 55 (01): : 28 - &
  • [47] The non-random location of human oncogenes and tumour suppressor genes
    Antonio, LD
    Widegren, B
    [J]. CARYOLOGIA, 2005, 58 (01) : 1 - 14
  • [48] Changing assembly rules during secondary succession: evidence for non-random patterns
    Csecserits, Aniko
    Halassy, Melinda
    Lhotsky, Barbara
    Redei, Tamas
    Somay, Laszlo
    Botta-Dukat, Zoltan
    [J]. BASIC AND APPLIED ECOLOGY, 2021, 52 : 46 - 56
  • [49] NON-RANDOM CHROMOSOMAL CHANGES IN CNS PRIMITIVE NEUROECTODERMAL TUMORS MEDULLOBLASTOMA (PNET-MB)
    BIEGEL, JA
    PACKER, RJ
    RORKE, LB
    EMANUEL, BS
    [J]. CANCER GENETICS AND CYTOGENETICS, 1989, 41 (02) : 228 - 228
  • [50] Comparative genomic hybridization reveals non-random chromosomal aberrations in early preinvasive cervical lesions
    Kirchhoff, M
    Rose, H
    Petersen, BL
    Maahr, J
    Gerdes, T
    Philip, J
    Lundsteen, C
    [J]. CANCER GENETICS AND CYTOGENETICS, 2001, 129 (01) : 47 - 51
12345