PI3K inhibition in preclinical models of HNSCC

被引:0
|
作者
Hedberg, Matthew Louis [1 ]
Li, Hua [1 ]
Zeng, Yan [1 ]
Grandis, Jennifer Rubin [1 ]
机构
[1] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA
关键词
D O I
10.1158/1538-8514.PI3K14-A39
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A39
引用
收藏
页数:2
相关论文
共 50 条
  • [21] PI3Kα inhibition reduces obesity in mice
    Lopez-Guadamillas, Elena
    Munoz-Martin, Maribel
    Martinez, Sonia
    Pastor, Joaquin
    Fernandez-Marcos, Pablo J.
    Serrano, Manuel
    AGING-US, 2016, 8 (11): : 2747 - 2753
  • [22] PI3Kβ inhibition: all that glitters is not gold
    Torti, Mauro
    BLOOD, 2015, 125 (05) : 750 - 751
  • [23] Inhibition of PI3K as a potential treatment for cancer
    Zuluaga, S.
    Suarez-Fueyo, A.
    Carrera, A. C.
    EJC SUPPLEMENTS, 2010, 8 (05): : 61 - 61
  • [24] The Role of PI3K Inhibition in Lymphoid Malignancies
    von Keudell, Gottfried
    Moskowitz, Alison J.
    CURRENT HEMATOLOGIC MALIGNANCY REPORTS, 2019, 14 (05) : 405 - 413
  • [25] The Role of PI3K Inhibition in Lymphoid Malignancies
    Gottfried von Keudell
    Alison J. Moskowitz
    Current Hematologic Malignancy Reports, 2019, 14 : 405 - 413
  • [26] Synergistic Effects of Concurrent Blockade of PI3K and MEK Pathways in Pancreatic Cancer Preclinical Models
    Zhong, Hua
    Sanchez, Cesar
    Spitrzer, Dirk
    Plambeck-Suess, Stacy
    Gibbs, Jesse
    Hawkins, Williams G.
    Denardo, David
    Gao, Feng
    Pufahl, Robert A.
    Lockhart, Albert C.
    Xu, Mai
    Linehan, David
    Weber, Jason
    Wang-Gillam, Andrea
    PLOS ONE, 2013, 8 (10):
  • [27] Dual inhibition of the PI3K and MAPK pathways enhances nab-paclitaxel/gemcitabine chemotherapy response in preclinical models of pancreatic cancer
    Awasthi, Niranjan
    Kronenberger, David
    Stefaniak, Alexis
    Hassan, Md Sazzad
    von Holzen, Urs
    Schwarz, Margaret A.
    Schwarz, Roderich E.
    CANCER LETTERS, 2019, 459 : 41 - 49
  • [28] Inhibition of PI3K and MEK in Combination With Radiation Therapy in Murine Model of Head and Neck Squamous Cell Carcinoma (HNSCC)
    Blas, K. G.
    Galoforo, S.
    Krueger, S. A.
    Wilson, T. G.
    Grills, I. S.
    Marples, B.
    Wilson, G. D.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2016, 96 (02): : E586 - E587
  • [29] PRECLINICAL IN VIVO EFFICACY OF PI3K PATHWAY INHIBITION IN PHILADELPHIA-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA
    Tasian, S. K.
    Li, Y.
    Ryan, T.
    Maude, S. L.
    Teachey, D. T.
    Loh, M. L.
    Hunger, S. P.
    Mullighan, C. G.
    Carroll, M.
    Grupp, S. A.
    PEDIATRIC BLOOD & CANCER, 2014, 61 : S168 - S168
  • [30] Feedback Suppression of PI3Kα Signaling in PTEN-Mutated Tumors Is Relieved by Selective Inhibition of PI3Kβ
    Schwartz, Sarit
    Wongvipat, John
    Trigwell, Cath B.
    Hancox, Urs
    Carver, Brett S.
    Rodrik-Outmezguine, Vanessa
    Will, Marie
    Yellen, Paige
    de Stanchina, Elisa
    Baselga, Jose
    Scher, Howard I.
    Barry, Simon T.
    Sawyers, Charles L.
    Chandarlapaty, Sarat
    Rosen, Neal
    CANCER CELL, 2015, 27 (01) : 109 - 122