Tacrolimus suppresses IL-12/IL23 p40 in Crohn's disease and heals fistulae refractory to anti-TNF-α therapy

被引:3
|
作者
Nakase, H. [1 ]
Matsuura, M. [1 ]
Uza, N. [1 ]
Chiba, T. [1 ]
机构
[1] Kyoto Univ, Grad Sch Med, Dept Gastroenterol & Hepatol, Kyoto, Japan
关键词
D O I
10.1111/j.1365-2036.2011.04587.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:979 / 980
页数:2
相关论文
共 50 条
  • [21] The bioactivity of IL-12: there's more to the story than p70 or p40
    Klinke, DJ
    Okino, M
    Shoda, L
    FASEB JOURNAL, 2003, 17 (07): : C131 - C131
  • [22] Minocycline treatment increases IL-12 p40 and s-VCAM in RRMS
    Zabad, R
    Metz, L
    Yong, W
    MULTIPLE SCLEROSIS, 2004, 10 (7032): : S259 - S260
  • [23] Induction of IL-2 by interleukin-12 p40 homodimer and IL-12, but not IL-23, in microglia and macrophages: Implications for multiple sclerosis
    Jana, Malabendu
    Mondal, Susanta
    Jana, Arundhati
    Pahan, Kalipada
    CYTOKINE, 2024, 174
  • [24] Functional analyses of the interaction of chicken interleukin 23 subunit p19 with IL-12 subunit p40 to form the IL-23 complex
    Anh Duc Truong
    Cong Thanh Hoang
    Hong, Yeojin.
    Lee, Janggeun
    Lee, Kyungbaek
    Lillehoj, Hyun S.
    Hong, Yeong Ho
    MOLECULAR IMMUNOLOGY, 2017, 92 : 54 - 67
  • [25] Preferential production of the IL-12(p40)/IL-23(p19) heterodimer by dendritic cells from human newborns
    Vanden Eijnden, S
    Goriely, S
    De Wit, D
    Goldman, M
    Willems, F
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2006, 36 (01) : 21 - 26
  • [26] 枸杞多糖对免疫抑制小鼠血清中IL-6、IL-10和IL-12/IL23 p40分泌水平的影响
    白学鹏
    孙鹏
    沈春秀
    杨荣敏
    王昀昕
    王佩
    李家兴
    苏春霞
    动物医学进展, 2019, 40 (07) : 49 - 51
  • [27] Remission of refractory Crohn's disease with anti-IL-12/23 therapy in a patient undergoing hemodialysis: A case report
    Spathakis, Michail
    Filidou, Eirini
    Kolios, George
    Papazoglou, Dimitrios
    Vradelis, Stergios
    HEMODIALYSIS INTERNATIONAL, 2023, 27 (03) : E41 - E44
  • [28] TNF and IL-12 are key mediators of ileitis in experimental Crohn's disease.
    Rivera-Nieves, J
    Pizarro, TT
    Moskaluk, CA
    Cominelli, F
    GASTROENTEROLOGY, 2000, 118 (04) : A873 - A873
  • [29] Serum Levels of TNF-α, IL-12/23p40, and IL-17 in Plaque Psoriasis and Their Correlation with Disease Severity
    Kyriakou, Aikaterini
    Patsatsi, Aikaterini
    Vyzantiadis, Timoleon-Achilleas
    Sotiriadis, Dimitrios
    JOURNAL OF IMMUNOLOGY RESEARCH, 2014, 2014
  • [30] A Rare Presentation of an IL-12/23 Antagonist in Crohn's Disease and Development of Sarcoidosis
    Singh, Rajiv
    Giang, Jimmy
    Ruzkowski, Charles
    Wisser, Kathryn
    Goff, John
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2020, 115 : S1224 - S1224