Probing friction in actin-based motility

被引:5
|
作者
Marcy, Yann [1 ]
Joanny, Jean-Francois [1 ]
Prost, Jacques [1 ]
Sykes, Cecile [1 ]
机构
[1] Inst Curie, CNRS, UMR168, Lab Physicochim Curie, F-75231 Paris 05, France
来源
NEW JOURNAL OF PHYSICS | 2007年 / 9卷
关键词
D O I
10.1088/1367-2630/9/11/431
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Actin dynamics are responsible for cell protrusion and certain intracellular movements. The transient attachment of the actin filaments to a moving surface generates a friction force that resists the movement. We probe here the dynamics of these attachments by inducing a stick-slip behavior via micromanipulation of a growing actin comet. We show that general principles of adhesion and friction can explain our observations.
引用
收藏
页数:7
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