Treatment of latent tuberculosis: Rational and regimens

被引:0
|
作者
Fraisse, P. [1 ]
机构
[1] Hop Univ Strasbourg, Grp TB, Serv Pneumol, Soc Pneumol Longue Francaise, F-67091 Strasbourg, France
关键词
Antitubercular agents; Isoniazid; Rifampin; Tuberculosis; Latent tuberculosis infection; ISONIAZID PREVENTIVE THERAPY; PULMONARY TUBERCULOSIS; INFECTION; RIFAMPIN; PROPHYLAXIS; CHILDREN; RISK; PYRAZINAMIDE; HEPATOTOXICITY; CONTACT;
D O I
10.1016/j.antinf.2011.07.002
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Treatment of latent tuberculosis infection is a key component of tuberculosis control programs. We describe here the benefit to risk ratio of this therapy at the individual and collective levels. Acceptance and adherence influence the efficiency of this treatment. A close follow-up of the patients is necessary to avoid toxicity. Isoniazid monotherapy for 6 to 9 months or isoniazid plus rifampin for 3 months are the most commonly used regimens. French guidelines are presented. (C) 2011 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:191 / 200
页数:10
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