Consensus guidelines and recommendations for infection prevention in multiple myeloma: a report from the International Myeloma Working Group

被引：6

作者：

Raje, Noopur S. ^{[1
]}

Anaissie, Elias ^{[3
]}

Kumar, Shaji K. ^{[4
]}

Lonial, Sagar ^{[5
]}

Martin, Thomas ^{[6
]}

Gertz, Morie A. ^{[4
]}

Krishnan, Amrita ^{[7
]}

Hari, Parameswaran ^{[8
]}

Ludwig, Heinz ^{[9
]}

O'Donnell, Elizabeth ^{[1
]}

Yee, Andrew ^{[1
]}

Kaufman, Jonathan L. ^{[5
]}

Cohen, Adam D. ^{[10
]}

Garderet, Laurent ^{[11
]}

Wechalekar, Ashutosh F. ^{[13
]}

Terpos, Evangelos ^{[14
]}

Khatry, Navin ^{[15
,16
]}

Niesvizky, Ruben ^{[17
]}

Yi, Qing ^{[18
]}

Joshua, Douglas E. ^{[19
]}

Saikia, Tapan ^{[20
]}

Leung, Nelson ^{[4
]}

Engelhardt, Monika ^{[21
]}

Mothy, Mohamad ^{[12
]}

Branagan, Andrew ^{[1
]}

Chari, Ajai ^{[22
,23
]}

Reiman, Anthony J. ^{[24
]}

Lipe, Brea ^{[25
]}

Richter, Joshua ^{[22
,23
]}

Rajkumar, S. Vincent ^{[4
]}

San Miguel, Jesus ^{[26
]}

Anderson, Kenneth C. ^{[2
]}

Stadtmauer, Edward A. ^{[10
]}

Prabhala, Rao H. ^{[2
]}

McCarthy, Phillip L. ^{[27
]}

Munshi, Nikhil C. ^{[2
]}

机构：

[1] Harvard Med Sch, Ctr Multiple Myeloma, Massachusetts Gen Hosp, Canc Ctr, Boston, MA 02114 USA

[2] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02114 USA

[3] CTI Clin Trial & Consulting Serv, Cincinnati, OH USA

[4] Mayo Clin, Div Hematol, Dept Internal Med, Rochester, MN USA

[5] Emory Univ, Sch Med, Winship Canc Inst, Dept Hematol & Med Oncol, Atlanta, GA USA

[6] Univ Calif San Francisco, UCSF Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA

[7] City Hope Natl Med Ctr, Judy & Bernard Briskin Myeloma Ctr, Duarte, CA USA

[8] Med Coll Wisconsin, Dept Med, Milwaukee, WI 53226 USA

[9] Clin Ottakring, Wilhelminen Canc Res Inst, Dept Med 1, Vienna, Austria

[10] Univ Penn, Abramson Canc Ctr, Philadelphia, PA 19104 USA

[11] Hop St Antoine, AP HP, Serv Hematol & Therapie Cellulaire, Paris, France

[12] Hop St Antoine, AP HP, Hematol Dept, Paris, France

[13] UCL, Natl Amyloidosis Ctr, London, England

[14] Natl & Kapodistrian Univ Athens, Dept Clin Therapeut, Athens, Greece

[15] Tata Mem Hosp, Dept Med Oncol, Mumbai, Maharashtra, India

[16] Homi Bhabha Natl Inst, Mumbai, Maharashtra, India

[17] Weill Cornell Med, Div Hematol & Oncol, New York, NY USA

[18] Houston Methodist Res Inst, Canc Ctr Basic Res Programs, Houston, TX USA

[19] Royal Prince Alfred Hosp, Inst Haematol, NSW Hlth Pathol, Camperdown, NSW, Australia

[20] Prince Aly Khan Hosp, Bone Marrow Transplantat & Med Oncol Dept, Mumbai, Maharashtra, India

[21] Univ Freiburg, Fac Med, Med Ctr, Freiburg, Germany

[22] Icahn Sch Med Mt Sinai, Dept Med Hematol & Med Oncol, New York, NY 10029 USA

[23] Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA

[24] St Johns Hosp, Dept Oncol, St John, NB, Canada

[25] Univ Rochester, Med Ctr, Dept Med, Rochester, NY 14642 USA

[26] Clin Univ Navarra, Ctr Invest Med Aplicada, Inst Invest Sanitaria Navarra, Pamplona, Spain

[27] Roswell Park Comprehens Canc Ctr, Dept Med, Buffalo, NY USA

来源：

LANCET HAEMATOLOGY | 2022年 / 9卷 / 02期

关键词：

STEM-CELL TRANSPLANTATION; PNEUMOCYSTIS-JIROVECII PNEUMONIA; BONE-MARROW-TRANSPLANTATION; HEPATITIS-C VIRUS; INTRAVENOUS IMMUNOGLOBULIN; HEMATOLOGICAL MALIGNANCIES; STREPTOCOCCUS-PNEUMONIAE; MONOCLONAL GAMMOPATHY; EARLY MORTALITY; AUTOLOGOUS TRANSPLANTATION;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Infection remains the leading cause of morbidity and mortality in patients with multiple myeloma because of the cumulative effect of disease, treatment, and host-related factors. Given that infectious risk is cumulative through the course of the disease, preventing infections is paramount. Optimal preventive strategies include vaccination against common pathogens, antimicrobial prophylaxis, infection control measures, and immunoglobulin replacement in a small subset of patients; however, there are no universally accepted guidelines for infection prevention. This Review provides a consensus statement from a panel of 36 experts with global representation, which was convened by The International Myeloma Society to review existing literature and current guidelines, address issues associated with the risk of infection and prevention of infectious complications in multiple myeloma in the context of emerging therapies, and offer recommendations for preventing these complications.

引用

页码：E143 / E161

页数：19

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