Colonic adenocarcinoma in a rhesus macaque (Macaca mulatta)

被引:6
|
作者
Johnson, EH [1 ]
Morgenstern, SE [1 ]
Perham, JM [1 ]
Barthold, SW [1 ]
机构
[1] YALE UNIV,SCH MED,COMPARAT MED SECT,NEW HAVEN,CT 06520
关键词
rhesus macaque; colonic adenocarcinoma; endometriosis; CA-125;
D O I
10.1111/j.1600-0684.1996.tb00040.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.
引用
收藏
页码:435 / 438
页数:4
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