1H-NMR studies of cerebrospinal fluid:: endogenous ethanol in patients with cervical myelopathy

被引：14
|
作者：
Meshitsuka, S [1 ]
Morio, Y
Nagashima, H
Teshima, R
机构：
[1] Tottori Univ, Fac Med, Dept Med Environmentol, Yonago, Tottori 6838503, Japan
[2] Tottori Univ, Fac Med, Dept Orthopaed Surg, Yonago, Tottori 6838504, Japan
来源：
CLINICA CHIMICA ACTA | 2001年 / 312卷 / 1-2期
关键词：
cerebrospinal fluid; cervical myelopathy; NMR; ethanol;
D O I：
10.1016/S0009-8981(01)00587-3
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Endogenous ethanol was observed by nuclear magnetic resonance spectroscopy in the course of screening for cerebrospinal fluid of the patients with cervical myelopathy. Ethanol was detected in 10 out of 20 patients. It seems likely that the presence of endogenous ethanol is related to the severity of myelopathy. Also, the concentration of ethanol was correlated with that of lactate in the cerebrospinal fluid. This implies that ethanol may be formed as the end product of glycolysis or in an unknown pathway in the case of severely insulted myelonic tissues. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：25 / 30
页数：6
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