The stabilization of type I collagen is important to applications of collagen protein. In this paper, the stabilization of type I collagen with Fe-gluconic acid has been studied by various methods such as UV-vis and IR spectra, CD and DSC etc. Gluconic acid can form a compound with ferrous sulphate which can improve the thermal stability of type I collagen to an extent greater than that of Fe alone. The reaction molar ratio was 1:3 between Fe and gluconic acid. The increase of thermal stability is owed to cross-link formation between the compound and collagen.
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All India Inst Med Sci, Dept Ophthalmol, Gorakhpur, Uttar Pradesh, IndiaAll India Inst Med Sci, Dept Ophthalmol, Gorakhpur, Uttar Pradesh, India
Agarwal, Richa
Jain, Parul
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Maulana Azad Med Coll, Dept Ophthalmol, Guru Nanak Eye Ctr, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Gorakhpur, Uttar Pradesh, India
Jain, Parul
Arora, Ritu
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Maulana Azad Med Coll, Dept Ophthalmol, Guru Nanak Eye Ctr, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Gorakhpur, Uttar Pradesh, India