Protein modeling of apical membrane antigen-1(AMA-1) of Plasmodium cynomolgi

被引：0
|
作者：
Mamatha, D. M. [1 ]
Nagalakshmamma, K. [1 ]
Rajesh, V. A. Dev [2 ]
Sheerin, V. S. [3 ]
机构：
[1] Sri Padmavathi Womens Univ, Dept Sericulture & Biosci, Tirupati 517502, Andhra Pradesh, India
[2] Dravidan Univ, Dept Bioinformat, Kuppam, India
[3] Sri Padmavathi Womens Univ, Dept Biosci, Tirupati 517502, Andhra Pradesh, India
来源：
AFRICAN JOURNAL OF BIOTECHNOLOGY | 2007年 / 6卷 / 22期
关键词：
protein model; AMA-1; apical membrane antigen-1; Plasmodium cynomolgi;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Apical membrane Antigen-1(AMA-1), an asexual blood stage antigen of Plasmodium cynomolgi, is an important candidate for testing as a component of malarial vaccine. The degree of conservation of AMA-1 sequences implies a conserved function for this molecule across different species of Plasmodium. Since the AMA-1 of plasmodium cyanomolgi is yet to be structured, the authors have generated a homology model of AMA-1 by using the Swiss-PDB server. The protein's conservity has been verified by performing multiple alignments using Bioedit and conserved domain database. The model was further checked for its correctness by predicting 2D and 3D structures, which validates the structure.
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收藏
页码：2628 / 2632
页数：5
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