Natural products from Peperomia: occurrence, biogenesis and bioactivity

被引:22
|
作者
Gutierrez, Yasmin Valero [1 ]
Yamaguchi, Lydia F. [1 ]
de Moraes, Marcilio M. [1 ]
Jeffrey, Christopher S. [2 ]
Kato, Massuo J. [1 ]
机构
[1] Univ Sao Paulo, Inst Chem, Res Support Ctr Mol Divers Nat Prod, Ave Prof Lineu Prestes 748, BR-05508000 Sao Paulo, SP, Brazil
[2] Univ Nevada, Dept Chem, Reno, NV 89557 USA
基金
美国国家科学基金会;
关键词
Piperaceae; Peperomia; Secondary metabolites; ESSENTIAL OIL COMPOSITION; CELL-SUSPENSION CULTURES; ABSOLUTE-CONFIGURATION; IN-VITRO; TETRAHYDROFURAN LIGNANS; ANTIBACTERIAL ACTIVITY; VOLATILE CONSTITUENTS; CHEMICAL-COMPOSITION; PHENOLIC-COMPOUNDS; PIPERACEAE;
D O I
10.1007/s11101-016-9461-5
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The Peperomia is one of the giant genus among Angiosperms with approximately 1600 species spread in the tropics. Their species are valuable as ornamental and several medicinal uses were described but their phytochemistry is poorly investigated compared to Piper (2000 species). In spite of this scarcity, typical classes of secondary metabolites isolated from their species are characterized as polyketides, meroterpenes, chromenes, phenylpropanoids, lignans and amides, among which 2-acylcyclohexane-1,3-diones, orsellinic acid-based meroterpenes and secolignans (peperomins) are very specific to Peperomia. The bioactivities of several compounds indicated their potential as antiparasites, antimicrobial, antiviral, cytotoxic agents against several tumoral strains and also as herbicides.
引用
收藏
页码:1009 / 1033
页数:25
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