Enantiomeric Natural Products: Occurrence and Biogenesis

被引：217

作者：

Finefield, Jennifer M. ^{[1
]}

Sherman, David H. ^{[2
,3
,4
,6
]}

Kreitman, Martin ^{[5
]}

Williams, Robert M. ^{[1
,7
]}

机构：

[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA

[2] Univ Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA

[3] Univ Michigan, Dept Med Chem, Ann Arbor, MI 48109 USA

[4] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

[5] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA

[6] Univ Michigan, Dept Microbiol & Immunol, Ann Arbor, MI 48109 USA

[7] Univ Colorado, Ctr Canc, Aurora, CO 80045 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 20期

基金：

美国国家卫生研究院;

关键词：

biosynthesis; enantioselectivity; isolation; natural products; STREPTOMYCES-COELICOLOR A3(2); PRENYLATED INDOLE ALKALOIDS; BIOSYNTHETIC GENE-CLUSTER; SAGE SALVIA-OFFICINALIS; MARINE-DERIVED FUNGUS; PYRAN RING FORMATION; FIR ABIES-GRANDIS; MEDICAGO-SATIVA L; SPONGE-IRCINIA SP; CDNA ISOLATION;

D O I：

10.1002/anie.201107204

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In nature, chiral natural products are usually produced in optically pure formhowever, occasionally both enantiomers are formed. These enantiomeric natural products can arise from a single species or from different genera and/or species. Extensive research has been carried out over the years in an attempt to understand the biogenesis of naturally occurring enantiomers; however, many fascinating puzzles and stereochemical anomalies still remain.

引用

页码：4802 / 4836

页数：35

共 50 条

[1] Enantiomeric natural products: Synthesis, biogenesis and evolutionary origins
Williams, Robert
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
[2] Natural products from Peperomia: occurrence, biogenesis and bioactivity
Gutierrez, Yasmin Valero
Yamaguchi, Lydia F.
de Moraes, Marcilio M.
Jeffrey, Christopher S.
Kato, Massuo J.
[J]. PHYTOCHEMISTRY REVIEWS, 2016, 15 (06) : 1009 - 1033
[3] Natural products from Peperomia: occurrence, biogenesis and bioactivity
Yasmin Valero Gutierrez
Lydia F. Yamaguchi
Marcilio M. de Moraes
Christopher S. Jeffrey
Massuo J. Kato
[J]. Phytochemistry Reviews, 2016, 15 : 1009 - 1033
[4] BIOGENESIS OF NATURAL PRODUCTS
BIRCH, AJ
[J]. NATURE, 1957, 180 (4588) : 679 - 681
[5] Natural Enantiomers: Occurrence, Biogenesis and Biological Properties
Yu, Jin-Hai
Yu, Zhi-Pu
Capon, Robert J.
Zhang, Hua
[J]. MOLECULES, 2022, 27 (04):
[6] Total Synthesis of Dimeric Natural Products Inspired by Biogenesis
Tsukano, Chihiro
[J]. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2013, 71 (09) : 946 - 947
[7] THE BIOGENESIS OF NATURAL PRODUCTS - ACETIC ACID AS A BUILDING UNIT IN THE FORMATION OF MOULD PRODUCTS
BIRCH, AJ
[J]. CHEMISTRY & INDUSTRY, 1957, (42) : 1370 - 1370
[8] Non-enzymatic reactions in biogenesis of fungal natural products
Kishimoto, Shinji
[J]. JOURNAL OF NATURAL MEDICINES, 2024, 78 (03) : 467 - 473
[9] Non-enzymatic reactions in biogenesis of fungal natural products
Shinji Kishimoto
[J]. Journal of Natural Medicines, 2024, 78 : 467 - 473
[10] Biogenesis and biomimetic chemistry: Can complex natural products be assembled spontaneously?
Gravel, Edmond
Poupon, Erwan
[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2008, 2008 (01) : 27 - 42

← 1 2 3 4 5 →