Results of PX-171-003-A0, part 1 of an open-label, single-arm, phase 2 study of carfilzomib in patients with relapsed and refractory multiple myeloma

被引：1

作者：

Siegel, D. ^{[1
]}

Vij, R. ^{[2
]}

Stewart, K. ^{[3
]}

Somlo, G. ^{[4
]}

Jakubowiak, A. ^{[5
]}

Kukreti, V. ^{[6
]}

Bahlis, N. ^{[7
]}

Singhal, S. ^{[8
]}

Wong, A. ^{[9
]}

Jagannath, S. ^{[10
]}

机构：

[1] Hackensack Univ, Med Ctr, John Theurer Canc Ctr, Hackensack, NJ USA

[2] Washington Univ, Sch Med, Div Hematol & Oncol, St Louis, MO USA

[3] Mayo Clin, Hematol Malignancies Program, Scottsdale, AZ USA

[4] City Hope Natl Med Ctr, Med Oncol, Duarte, CA USA

[5] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[6] Princess Margaret Hosp, Toronto, ON M4X 1K9, Canada

[7] Univ Calgary, Tom Baker Canc Ctr, Calgary, AB, Canada

[8] Northwestern Univ, Robert Lurie Comprehens Canc Ctr, Chicago, IL 60611 USA

[9] Proteolix Inc, Clin Dev, San Francisco, CA USA

[10] St Vincents Comprehens Canc Ctr, Multiple Myeloma & Transplant Program, New York, NY USA

来源：

EJC SUPPLEMENTS | 2009年 / 7卷 / 02期

关键词：

D O I：

10.1016/S1359-6349(09)71927-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：571 / 571

页数：1

共 50 条

[1] Final results of PX-171-003-A0, part 1 of an open-label, single-arm, phase II study of carfilzomib (CFZ) in patients (pts) with relapsed and refractory multiple myeloma (MM)
Jagannath, S.
Vij, R.
Stewart, K.
Somlo, G.
Jakubowiak, A.
Trudel, S.
Schwartz, R.
Siegel, D.
Kunkel, L.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
[2] An Open-Label Single-Arm Pilot Phase II Study (PX-171-003-A0) of Low-Dose, Single-Agent Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma
Jagannath, Sundar
Vij, Ravi
Stewart, A. Keith
Trudel, Suzanne
Jakubowiak, Andrzej J.
Reiman, Tony
Somlo, George
Bahlis, Nizar
Lonial, Sagar
Kunkel, Lori A.
Wong, Alvin
Orlowski, Robert Z.
Siegel, David S.
[J]. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2012, 12 (05): : 310 - 318
[3] Initial Results of PX-171-003, An Open-Label, Single-Arm, Phase II Study of Carfilzomib (CFZ) in Patients with Relapsed and Refractory Multiple Myeloma (MM)
Jagannath, Sundar
Vij, Ravi
Stewart, A. Keith
Somlo, George
Jakubowiak, Andrzej
Reiman, Tony
Trudel, Suzanne
Taylor, Jessica
Fuhrman, Diana
Cruickshank, Scott
Schwartz, Richard
Kunkel, Lori
Siegel, David
[J]. BLOOD, 2008, 112 (11) : 319 - 319
[4] Results of PX-171-003-A1, An Open-Label, Single-Arm, Phase 2 (Ph 2) Study of Carfilzomib (CFZ) In Patients (pts) with Relapsed and Refractory Multiple Myeloma (MM)
Samuel, David
Martin, Thomas
Wang, Michael
Vij, Ravi
Jakubowiak, Andrzej J.
Jagannath, Sundar
Lonial, Sagar
Kukreti, Vishal
Bahlis, Nizar J.
Alsina, Melissa
Chanan-Khan, Asher A.
Somlo, George
Buadi, Francis
Reu, Frederic J.
Zonder, Jeffrey A.
Song, Kevin
Stadtmauer, Edward
Wong, Alvin F.
Vallone, Marcy
Chang, Yu-Lin
Kauffman, Michael
Orlowski, Robert Z.
Stewart, A. Keith
Singhal, Seema B.
[J]. BLOOD, 2010, 116 (21) : 433 - 433
[5] An open-label, single-arm, phase 2 (PX-171-004) study of single-agent carfilzomib in bortezomib-naive patients with relapsed and/or refractory multiple myeloma
Vij, Ravi
Wang, Michael
Kaufman, Jonathan L.
Lonial, Sagar
Jakubowiak, Andrzej J.
Stewart, A. Keith
Kukreti, Vishal
Jagannath, Sundar
McDonagh, Kevin T.
Alsina, Melissa
Bahlis, Nizar J.
Reu, Frederic J.
Gabrail, Nashat Y.
Belch, Andrew
Matous, Jeffrey V.
Lee, Peter
Rosen, Peter
Sebag, Michael
Vesole, David H.
Kunkel, Lori A.
Wear, Sandra M.
Wong, Alvin F.
Orlowski, Robert Z.
Siegel, David S.
[J]. BLOOD, 2012, 119 (24) : 5661 - 5670
[6] Initial Results of PX-171-004, An Open-Label, Single-Arm, Phase II Study of Carfilzomib (CFZ) in Patients with Relapsed Myeloma (MM)
Vu, Ravi
Wang, Michael
Orlowski, Robert
Stewart, A. Keith
Jagannath, Sundar
Kukreti, Vishal
Taylor, Jessica
Fuhrman, Diana
Cruickshank, Scott
Schwartz, Richard
Kunkel, Lori
Siegel, David
[J]. BLOOD, 2008, 112 (11) : 320 - 320
[7] Phase II Study of Carfilzomib in Patients with Relapsed and Refractory Multiple Myeloma (PX-171-003)
Jagannath, S.
Vij, R.
Stewart, A. K.
Somlo, G.
Jakubowiak, A.
Reiman, T.
Trudel, S.
Taylor, J.
Fuhrman, D.
Cruickshank, S.
Schwartz, R.
Kunkel, L.
Siegel, D.
[J]. CLINICAL LYMPHOMA & MYELOMA, 2009, 9 : S61 - S61
[8] Aphase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
Siegel, David S.
Martin, Thomas
Wang, Michael
Vij, Ravi
Jakubowiak, Andrzej J.
Lonial, Sagar
Trudel, Suzanne
Kukreti, Vishal
Bahlis, Nizar
Alsina, Melissa
Chanan-Khan, Asher
Buadi, Francis
Reu, Frederic J.
Somlo, George
Zonder, Jeffrey
Song, Kevin
Stewart, A. Keith
Stadtmauer, Edward
Kunkel, Lori
Wear, Sandra
Wong, Alvin F.
Orlowski, Robert Z.
Jagannath, Sundar
[J]. BLOOD, 2012, 120 (14) : 2817 - 2825
[9] A phase ll study (PX-171-003-A1) of single-agent carfilzomib in patients with advanced relapsed and refractory multiple myeloma
Siegel, D.
Martin, T.
Wang, M.
Vij, R.
Jakubowiak, A.
Lonial, S.
Trudel, S.
Kukreti, V
Bahlis, N.
Alsina, M.
Chanan-Khan, A.
Buadi, F.
Reu, F.
Somlo, G.
Zonder, J.
Stewart, A. K.
Stadtmauer, E.
Harrison, B.
Rajangam, K.
Orlowski, R.
Jagannath, S.
[J]. ONKOLOGIE, 2013, 36 : 38 - 39
[10] LONG-TERM FOLLOW-UP IN PX-171-003-A1, AN OPEN-LABEL, SINGLE-ARM PHASE (PH) 2 STUDY OF CARFILZOMIB (CFZ) IN PATIENTS (PTS) WITH RELAPSED AND REFRACTORY MULTIPLE MYELOMA (R/R MM): ANALYSIS BY SUBGROUPS OF INTEREST
Siegel, D. S.
Martin, T.
Wang, M.
Vij, R.
Jakubowiak, A. J.
Lonial, S.
Kukreti, V.
Alsina, M.
Somlo, G.
Kunkel, L.
Wong, A.
Orlowski, R. Z.
Stewart, A. K.
Singhal, S.
Jagannath, S.
[J]. ANNALS OF ONCOLOGY, 2011, 22 : 200 - 200

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