Results of PX-171-003-A1, An Open-Label, Single-Arm, Phase 2 (Ph 2) Study of Carfilzomib (CFZ) In Patients (pts) with Relapsed and Refractory Multiple Myeloma (MM)

被引：0

作者：

Samuel, David ^{[1
]}

Martin, Thomas ^{[2
]}

Wang, Michael

Vij, Ravi ^{[4
]}

Jakubowiak, Andrzej J. ^{[5
]}

Jagannath, Sundar ^{[6
]}

Lonial, Sagar ^{[7
]}

Kukreti, Vishal ^{[8
]}

Bahlis, Nizar J. ^{[9
]}

Alsina, Melissa ^{[10
]}

Chanan-Khan, Asher A. ^{[11
]}

Somlo, George ^{[12
]}

Buadi, Francis ^{[13
]}

Reu, Frederic J. ^{[14
]}

Zonder, Jeffrey A. ^{[15
]}

Song, Kevin ^{[16
]}

Stadtmauer, Edward ^{[17
]}

Wong, Alvin F. ^{[18
]}

Vallone, Marcy ^{[18
]}

Chang, Yu-Lin ^{[18
]}

Kauffman, Michael ^{[18
]}

Orlowski, Robert Z. ^{[3
]}

Stewart, A. Keith ^{[19
]}

Singhal, Seema B. ^{[20
]}

机构：

[1] Hackensack Univ, Med Ctr, John Theurer Canc Ctr, Hackensack, NJ USA

[2] Univ San Francisco, San Francisco, CA 94117 USA

[3] Univ Texas MD Anderson Canc Ctr, Dept Lymphoma Myeloma, Houston, TX 77030 USA

[4] Washington Univ, Sch Med, Div Oncol, St Louis, MO USA

[5] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[6] Mt Sinai Med Ctr, Multiple Myeloma Program, New York, NY 10029 USA

[7] Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USA

[8] Princess Margaret Hosp, Div Hematol Oncol, Toronto, ON M4X 1K9, Canada

[9] Univ Calgary, Div Hematol, Calgary, AB, Canada

[10] Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33682 USA

[11] Roswell Pk Canc Inst, Buffalo, NY 14263 USA

[12] City Hope Natl Med Ctr, Duarte, CA 91010 USA

[13] Mayo Clin, Dept Internal Med, Div Hematol, Rochester, MN USA

[14] Taussig Canc Ctr, Cleveland, OH USA

[15] Wayne State Univ, Karmanos Canc Inst, Detroit, MI USA

[16] Univ British Columbia, Div Hematol & Leukemia BMT, Vancouver, BC V5Z 1M9, Canada

[17] Univ Penn, Philadelphia, PA 19104 USA

[18] Onyx Pharmaceut, Emeryville, CA USA

[19] Mayo Clin Arizona, Scottsdale, AZ USA

[20] Northwestern Univ, Feinberg Sch Med, Div Hem Onc, Chicago, IL USA

[21] Multiple Myeloma Res Consortium, Norwalk, CT USA

来源：

BLOOD | 2010年 / 116卷 / 21期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：433 / 433

页数：1

共 50 条

[1] Initial Results of PX-171-003, An Open-Label, Single-Arm, Phase II Study of Carfilzomib (CFZ) in Patients with Relapsed and Refractory Multiple Myeloma (MM)
Jagannath, Sundar
Vij, Ravi
Stewart, A. Keith
Somlo, George
Jakubowiak, Andrzej
Reiman, Tony
Trudel, Suzanne
Taylor, Jessica
Fuhrman, Diana
Cruickshank, Scott
Schwartz, Richard
Kunkel, Lori
Siegel, David
[J]. BLOOD, 2008, 112 (11) : 319 - 319
[2] Final results of PX-171-003-A0, part 1 of an open-label, single-arm, phase II study of carfilzomib (CFZ) in patients (pts) with relapsed and refractory multiple myeloma (MM)
Jagannath, S.
Vij, R.
Stewart, K.
Somlo, G.
Jakubowiak, A.
Trudel, S.
Schwartz, R.
Siegel, D.
Kunkel, L.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
[3] LONG-TERM FOLLOW-UP IN PX-171-003-A1, AN OPEN-LABEL, SINGLE-ARM PHASE (PH) 2 STUDY OF CARFILZOMIB (CFZ) IN PATIENTS (PTS) WITH RELAPSED AND REFRACTORY MULTIPLE MYELOMA (R/R MM): ANALYSIS BY SUBGROUPS OF INTEREST
Siegel, D. S.
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Wang, M.
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Jakubowiak, A. J.
Lonial, S.
Kukreti, V.
Alsina, M.
Somlo, G.
Kunkel, L.
Wong, A.
Orlowski, R. Z.
Stewart, A. K.
Singhal, S.
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[J]. ANNALS OF ONCOLOGY, 2011, 22 : 200 - 200
[4] Results of PX-171-003-A0, part 1 of an open-label, single-arm, phase 2 study of carfilzomib in patients with relapsed and refractory multiple myeloma
Siegel, D.
Vij, R.
Stewart, K.
Somlo, G.
Jakubowiak, A.
Kukreti, V.
Bahlis, N.
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[J]. EJC SUPPLEMENTS, 2009, 7 (02): : 571 - 571
[5] PX-171-003-A1, an open-label, single-arm, phase (Ph) II study of carfilzomib (CFZ) in patients (pts) with relapsed and refractory multiple myeloma (R/R MM): Long-term follow-up and subgroup analysis
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[J]. JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
[6] Initial Results of PX-171-004, An Open-Label, Single-Arm, Phase II Study of Carfilzomib (CFZ) in Patients with Relapsed Myeloma (MM)
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[J]. BLOOD, 2008, 112 (11) : 320 - 320
[7] Aphase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
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Alsina, Melissa
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Buadi, Francis
Reu, Frederic J.
Somlo, George
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Wear, Sandra
Wong, Alvin F.
Orlowski, Robert Z.
Jagannath, Sundar
[J]. BLOOD, 2012, 120 (14) : 2817 - 2825
[8] UPDATED RESULTS FOR BORTEZOMIB (BTZ)-NAIVE PATIENTS (PTS) ENROLLED IN PX-171-004, AN ONGOING OPEN-LABEL, PHASE (PH) 2 STUDY OF CARFILZOMIB (CFZ), IN RELAPSED MULTIPLE MYELOMA (MM)
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Alsina, M.
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Le, M. H.
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Wang, M.
[J]. ANNALS OF ONCOLOGY, 2011, 22 : 200 - 201
[9] A phase ll study (PX-171-003-A1) of single-agent carfilzomib in patients with advanced relapsed and refractory multiple myeloma
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Trudel, S.
Kukreti, V
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Alsina, M.
Chanan-Khan, A.
Buadi, F.
Reu, F.
Somlo, G.
Zonder, J.
Stewart, A. K.
Stadtmauer, E.
Harrison, B.
Rajangam, K.
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[J]. ONKOLOGIE, 2013, 36 : 38 - 39
[10] A single-arm, open-label, multicenter phase I/II study of the combination of panobinostat (pan) and carfilzomib (cfz) in patients (pts) with relapsed/refractory multiple myeloma (RR MM).
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Patel, Manish R.
Hart, Lowell L.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)

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