Copper(II)-catalyzed exo and enantioselective cycloadditions of azomethine imines

被引：110
|
作者：
Sibi, Mukund P. [1 ]
Rane, Digamber [1 ]
Stanley, Levi M. [1 ]
Soeta, Takahiro [1 ]
机构：
[1] N Dakota State Univ, Dept Chem, Fargo, ND 58105 USA
来源：
ORGANIC LETTERS | 2008年 / 10卷 / 14期
关键词：
D O I：
10.1021/ol800904t
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A strategy for exo and enantioselective 1,3-dipolar cycloaddition of azomethine imines to 2-acryloyl-3-pyrazolidinone is described. The corresponding cycloadducts are isolated with high diastereoselectivities (up to >96:4 exo/endo) and enantioselectivities (up to 98% ee).
引用
收藏
页码：2971 / 2974
页数：4
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