No Increased Risk of Inflammatory Bowel Disease Among Secukinumab-Treated Patients with Moderate to Severe Psoriasis, Psoriatic Arthritis, or Ankylosing Spondylitis: Data from 14 Phase 2 and Phase 3 Clinical Studies

被引：0
|
作者：
Deodhar, Atul A. [1 ]
Schreiber, Stefan [2 ]
Gandhi, Kunal [3 ]
Fox, Todd [4 ]
Gaillez, Corine [4 ]
Karyekar, Chetan [3 ]
机构：
[1] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
[2] Christian Albrechts Univ Kiel, Kiel, Germany
[3] Novartis Pharmaceut, E Hanover, NJ USA
[4] Novartis Pharma AG, Basel, Switzerland
来源：
ARTHRITIS & RHEUMATOLOGY | 2016年 / 68卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
962
引用
收藏
页数：3
相关论文
共 50 条
  • [21] Secukinumab-treated subjects experience low rates of Candida and recurrent Candida infections: A pooled analysis from 10 phase 2 and 3 clinical studies in psoriasis
    Conrad, Curdin
    Reich, Kristian
    Blauvelt, Andrew
    Armstrong, April
    Krueger, James
    Gong, Yankun
    Milutinovic, Marina
    Langley, Richard
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 74 (05) : AB274 - AB274
  • [22] Secukinumab decreases inflammation as measured by a biomarker hsCRP in subjects with moderate-to-severe plaque psoriasis and concomitant psoriatic arthritis: subanalyses from two phase 3 studies
    Philipp, S.
    Gottlieb, A. B.
    Langley, R. G.
    Sigurgeirsson, B.
    Blauvelt, A.
    Gong, Y.
    Papavassilis, C.
    Mpofu, S.
    EXPERIMENTAL DERMATOLOGY, 2015, 24 (03) : E27 - E27
  • [23] Secukinumab decreases inflammation as measured by a Biomarker hsCRP in subjects with moderate-to-severe plaque psoriasis and concomitant psoriatic arthritis: subanalyses from two phase 3 studies
    Shumack, S.
    Gottlieb, A. B.
    Langley, R. G.
    Sigurgeirsson, B.
    Blauvelt, A.
    Philipp, S.
    Gong, Y.
    Papavassilis, C.
    Mpofu, S.
    AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2015, 56 : 67 - 67
  • [24] SECUKINUMAB SIGNIFICANTLY REDUCES PSORIASIS BURDEN IN PATIENTS WITH PSORIATIC ARTHRITIS: RESULTS FROM THE PHASE 3 FUTURE 2 STUDY
    Gottlieb, A.
    McInnes, I. B.
    Mease, P.
    Rahman, P.
    Kandala, S.
    Patekar, M.
    Mpofu, S.
    ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 : 349 - 350
  • [25] Lack of tuberculosis reactivation in 12,319 patients with psoriasis, psoriatic arthritis, or ankylosing spondylitis treated with secukinumab: An ad hoc analysis of pooled safety data from 28 clinical trials
    Elewski, Boni
    Baddley, John W.
    Deodhar, Atul
    Magrey, Marina
    Rich, Phoebe
    Soriano, Enrique
    Soung, Jennifer
    Bao, Weibin
    Patekar, Manmath
    Lebwohl, Mark
    Sharma, Abhishek
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 83 (06) : AB33 - AB33
  • [26] Secukinumab effects on cardiovascular risk factors in patients with psoriasis, psoriatic arthritis and axial spondyloarthritis: Results from post hoc analyses of pooled data from 19 phase 3/4 clinical studies
    Merola, Joseph F.
    McInnes, Iain B.
    Deodhar, Atul A.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2022, 87 (03) : AB107 - AB107
  • [27] INCIDENCE OF SERIOUS GASTROINTESTINAL EVENTS AND INFLAMMATORY BOWEL DISEASE AMONG TILDRAKIZUMAB-TREATED PATIENTS WITH MODERATE TO SEVERE PLAQUE PSORIASIS: DATA FROM 3 LARGE RANDOMISED CLINICAL TRIALS
    Gooderham, M.
    Elewski, B. E.
    Pariser, D. M.
    Sofen, H.
    Mendelsohn, A. M.
    Cichanowitz, N.
    Li, Q.
    La Rosa, C.
    ANNALS OF THE RHEUMATIC DISEASES, 2018, 77 : 364 - 364
  • [28] Incidence of Serious Gastrointestinal Events and Inflammatory Bowel Disease Among Tildrakizumab-Treated Patients with Moderate to Severe Plaque Psoriasis: Data from 3 Large Randomized Clinical Trials
    Gooderham, Melinda
    Elewski, Boni E.
    Pariser, David M.
    Sofen, Howard
    Mendelsohn, Alan M.
    Cichanowitz, Nicole
    Li, Qing
    ARTHRITIS & RHEUMATOLOGY, 2018, 70
  • [29] LACK OF REACTIVATION OF TUBERCULOSIS IN 12,319 PATIENTS WITH PSORIASIS, PSORIATIC ARTHRITIS AND ANKYLOSING SPONDYLITIS TREATED wail SECUKINUMAB: AN AD HOC ANALYSIS OF POOLED SAFETY DATA FROM 28 CLINICAL TRIALS
    Soriano, Enrique R.
    Elewski, Boni
    Baddley, John
    Deodhar, Atul
    Magrey, Marina
    Rich, Phoebe
    Soung, Jennifer
    Sharma, Abhishek
    Bao, Weibin
    Patekar, Manmath
    Lebwohl, Mark
    JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2020, 26 : 65 - 66
  • [30] Secukinumab Effects on Cardiometabolic Risk and Systemic Inflammation in Patients with Psoriasis, Psoriatic Arthritis and Axial Spondyloarthritis: Results from Post Hoc Analyses of Pooled Data from 19 Phase 3/4 Clinical Studies
    Merola, Joseph
    McInnes, Iain
    Deodhar, Atul
    Quebe-Fehling, Erhard
    Aassi, Maher
    Peine, Michael
    Mehta, Nehal
    ARTHRITIS & RHEUMATOLOGY, 2021, 73 : 3837 - 3839
12345