Intra-arterial urokinase for acute ischemic stroke: Factors associated with complications

被引：8
|
作者：
Tirschwell, DL
Coplin, WM
Becker, KJ
Vogelzang, P
Eskridge, J
Haynor, D
Cohen, W
Newell, D
Winn, HR
Longstreth, WT
机构：
[1] Univ Washington, Dept Neurol, Seattle, WA 98195 USA
[2] Univ Washington, Dept Neuroradiol, Seattle, WA 98195 USA
[3] Univ Washington, Dept Neurol Surg, Seattle, WA 98195 USA
[4] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA
[5] Seattle Radiologists, Seattle, WA USA
[6] Wayne State Univ, Dept Neurol, Detroit, MI USA
[7] Wayne State Univ, Dept Neurosurg, Detroit, MI USA
来源：
NEUROLOGY | 2001年 / 57卷 / 06期
关键词：
D O I：
10.1212/WNL.57.6.1100
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors abstracted the records of 43 patients treated with intra-arterial urokinase for acute ischemic stroke to identify predictors of serious complications. Sixteen (37%) had such a complication. Higher urokinase dose (>1.5 X 10(6) U), higher mean arterial blood pressure before treatment (> 130 mm Hg), basilar occlusive strokes, and severe strokes were most predictive of these complications. Although urokinase is no longer manufactured, these findings identify patients at risk for complications from other intra-arterial thrombolytics.
引用
收藏
页码：1100 / 1103
页数：4
相关论文
共 50 条
  • [41] Endovascular treatment and intra-arterial thrombolysis in acute ischemic stroke
    Escudero, D.
    Molina, R.
    Vina, L.
    Rodriguez, P.
    Marques, L.
    Fernandez, E.
    Forcelledo, L.
    Otero, J.
    Taboada, F.
    Vega, P.
    Murias, E.
    Gil, A.
    [J]. MEDICINA INTENSIVA, 2010, 34 (06) : 370 - 378
  • [42] Workflow and factors associated with delay in the delivery of intra-arterial treatment for acute ischemic stroke in the MR CLEAN trial
    Venema, Esmee
    Boodt, Nikki
    Berkhemer, Olvert A.
    Rood, Pleunie P. M.
    van Zwam, Wim H.
    van Oostenbrugge, Robert J.
    van der Lugt, Aad
    Roos, Yvo B. W. E. M.
    Majoie, Charles B. L. M.
    Lingsma, Hester F.
    Dippel, Diederik W. J.
    [J]. JOURNAL OF NEUROINTERVENTIONAL SURGERY, 2018, 10 (05) : 424 - U19
  • [43] Intra arterial urokinase for acute ischemic stroke: Experience with 23 patients
    Tirschwell, DL
    Coplin, WM
    Longstreth, WT
    Haynor, D
    Eskridge, J
    Newell, DW
    Winn, HR
    [J]. NEUROLOGY, 1997, 48 (03) : 33003 - 33003
  • [44] Outcome in Acute Stroke with Different Intra-Arterial Infusion Rate of Urokinase on Thrombolysis
    Gan, X.
    Luo, Y.
    Ling, F.
    Ji, X.
    Chen, J.
    Ding, Y.
    [J]. INTERVENTIONAL NEURORADIOLOGY, 2010, 16 (03) : 290 - 296
  • [45] Factors associated with rapid neurological improvement 24 h following intra-arterial thrombolytic treatment for acute ischemic stroke
    Christoforidis, Gregorgy
    Mohammad, Yousef M.
    Khadir, Mohammed
    Yang, Ming
    Slivka, Andrew P.
    [J]. JOURNAL OF NEUROINTERVENTIONAL SURGERY, 2013, 5 (01) : 35 - 39
  • [46] Quality of Life after Intra-arterial Therapy for Acute Ischemic Stroke
    Cortez, Melissa M.
    Wilder, Michael J.
    McFadden, Molly
    Majersik, Jennifer J.
    [J]. JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2014, 23 (07): : 1890 - 1896
  • [47] Intra-arterial thrombolysis for acute ischemic stroke: Our institutional experience
    Narayana, R. V.
    Pati, Rajesh
    Dalai, Sibasankar
    [J]. INDIAN JOURNAL OF NEUROSURGERY, 2012, 1 (01) : 38 - 40
  • [48] Intra-Arterial Treatment for Acute Ischemic Stroke: A Meta-Analysis
    Lakhan, Shaheen
    McClellan, Walther
    Truc Nguyen
    [J]. NEUROLOGY, 2016, 86
  • [49] Intra-arterial thrombolysis and thrombectomy for acute ischemic stroke: technique and results
    Kan, P. T.
    Orion, D.
    Yashar, P.
    Levy, E. I.
    [J]. JOURNAL OF NEUROSURGICAL SCIENCES, 2011, 55 (02) : 151 - 160
  • [50] INTRA-ARTERIAL TRANSPLANTATION OF MESENCHYMAL STEM CELLS IN ISCHEMIC STROKE: PREVENTING THE COMPLICATIONS
    Namestnikova, D.
    Gubskiy, I.
    Gabashvili, A.
    Melnikov, P.
    Voitkowskaya, K.
    Sukhinich, K.
    Kutasheva, A.
    Vakhrushev, I.
    Burunova, V.
    Gubsky, L.
    Yarygin, K.
    [J]. INTERNATIONAL JOURNAL OF STROKE, 2016, 11 (SUPP 3) : 23 - 23
12345