Effect of an exclusive human milk diet on feeding tolerance in preterm infants

被引：2

作者：

El-Fadeel, Hiba ^{[1
]}

Velumula, Pradeep ^{[1
]}

Lulic-Botica, Mirjana ^{[2
]}

Natarajan, Girija ^{[3
]}

Thomas, Ronald ^{[3
]}

Botica, Gabriella ^{[4
]}

Bajaj, Monika ^{[3
]}

机构：

[1] Childrens Hosp Michigan, Dept Pediat, Detroit, MI 48201 USA

[2] Wayne State Univ, Dept Pharm, Detroit, MI 48201 USA

[3] Cent Michigan Univ, Dept Pediat, Detroit, MI 48201 USA

[4] Wayne State Univ, Detroit, MI 48201 USA

来源：

JOURNAL OF PERINATOLOGY | 2022年 / 42卷 / 08期

关键词：

NECROTIZING ENTEROCOLITIS; INTESTINAL FAILURE; BREAST-MILK; MORTALITY; GROWTH;

D O I：

10.1038/s41372-022-01348-y

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVE: To compare the time to full enteral feeds in preterm infants fed exclusive human milk (EHM) - mother's own milk (MOM) fortified with human milk-based fortifier (HMBF), to those who received partial human milk (PHM) - MOM fortified with bovine milk-based fortifier (BMBF), and exclusive formula. STUDY DESIGN: A single-center retrospective study of infants with birth weight <1250 g from 2013 to 2018. Data on feeding, growth and other short-term neonatal morbidities were collected. RESULTS: On regression analysis, time to full enteral feeds was significantly higher in PHM compared to EHM group (beta-coefficient 4.14, 95% CI 0.00-8.29) and formula-fed group compared to EHM (beta-coefficient 4.3, 95% CI 0.32-8.20). No significant differences in growth velocity, length of stay and other morbidities were found between the groups. CONCLUSION: Infants in EHM had better feeding tolerance and reached their enteral feed goals sooner compared to PHM and formula-fed groups.

引用

页码：1070 / 1075

页数：6

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