Antibiotic-loaded bone cement in total joint arthroplasty

被引：1

作者：

Soares, Daniel ^{[1
]}

Leite, Pedro ^{[1
]}

Barreira, Pedro ^{[1
]}

Aido, Ricardo ^{[1
]}

Sousa, Ricardo ^{[1
]}

机构：

[1] Hosp St Antonio, Ctr Hosp Porto, Dept Orthopaed, P-4099001 Oporto, Portugal

来源：

ACTA ORTHOPAEDICA BELGICA | 2015年 / 81卷 / 02期

关键词：

bone cements; arthroplasty; replacement; prosthesis-related infections; anti-bacterial agents; administration & dosage; TOTAL-KNEE ARTHROPLASTY; TOTAL HIP-ARTHROPLASTY; CEFUROXIME-IMPREGNATED CEMENT; 2-STAGE REVISION; ANTIBACTERIAL ACTIVITY; INFECTION; SPACERS; PROPHYLAXIS; DAPTOMYCIN; VANCOMYCIN;

D O I：

暂无

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Periprosthetic joint infection is a devastating complication after total joint replacement. Prevention is mandatory and systemic antibiotic prophylaxis is nowadays a recognized cornerstone. Further addition of local antibiotics eluting from bone cement is a real possibility but its routine use is controversial. Pros and cons of its routine use in primary and revision total joint arthroplasty will be discussed. Cement spacers carrying high doses of antibiotic(s) are currently accepted during two-stage treatment of infected prosthetic joints. Several issues such as alternatives to classic antibiotics, optimal dosages and others will also be explored.

引用

页码：184 / 190

页数：7

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