LIFE COURSE SOCIOECONOMIC POSITION, ALLOSTATIC LOAD, AND INCIDENCE OF TYPE 2 DIABETES AMONG AFRICAN AMERICAN ADULTS: THE JACKSON HEART STUDY, 2000-04 TO 2012
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作者:
Beckles, Gloria L.
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Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USACtr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
Beckles, Gloria L.
[1
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Bullard, Kai McKeever
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Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USACtr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
Bullard, Kai McKeever
[1
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Saydah, Sharon
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Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USACtr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
Saydah, Sharon
[1
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Imperatore, Giuseppina
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Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USACtr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
Imperatore, Giuseppina
[1
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Loustalot, Fleetwood
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Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USACtr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
Loustalot, Fleetwood
[2
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Correa, Adolfo
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Univ Mississippi, Med Ctr, Jackson, MS 39216 USACtr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
Correa, Adolfo
[3
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机构:
[1] Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
[2] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
[3] Univ Mississippi, Med Ctr, Jackson, MS 39216 USA
Objective: We examined whether life course socioeconomic position (SEP) was associated with incidence of type 2 diabetes (t2DM) among African Americans. Design: Secondary analysis of data from the Jackson Heart Study, 2000-04 to 2012, using Cox proportional hazard regression to estimate hazard ratios (HR) with 95% CI for t2DM incidence by measures of life course SEP. Participants: Sample of 4,012 nondiabetic adults aged 25-84 years at baseline. Outcome Measure: Incident t2DM identified by self-report, hemoglobin A1c >= 6.5%, fasting plasma glucose >= 126 mg/dL, or use of diabetes medication. Results: During 7.9 years of follow-up, 486 participants developed t2DM (incidence rate 15.2/1000 person-years, 95% CI: 13.9-16.6). Among women, but not men, childhood SEP was inversely associated with t2DM incidence (HR=.97, 95% Cl: .94-.99) but was no longer associated with adjustment for adult SEP or t2DM risk factors. Upward SEP mobility increased the hazard for t2DM incidence (adjusted HR=1.52, 95% CI: 1.05-2.21) among women only. Life course allostatic load (AL) did not explain the SEP-t2DM association in either sex. Conclusions: Childhood SEP and upward social mobility may influence t2DM incidence in African American women but not in men.
机构:
China Med Univ Hosp, Dept Med Res, Taichung, Taiwan
China Med Univ, Grad Inst Hlth Care Adm, Coll Publ Hlth, Taichung, TaiwanChina Med Univ Hosp, Dept Family Med, Taichung, Taiwan
Hsiao, Chih-Yi
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Liu, Chiu-Shong
Yang, Sing-Yu
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China Med Univ, Grad Inst Biostat, Coll Publ Hlth, Taichung, TaiwanChina Med Univ Hosp, Dept Family Med, Taichung, Taiwan
Yang, Sing-Yu
Lee, Cheng-Chun
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China Med Univ, Sch Med, Coll Med, Taichung, Taiwan
China Med Univ Hosp, Dept Neurol, Taichung, TaiwanChina Med Univ Hosp, Dept Family Med, Taichung, Taiwan
机构:
Univ Copenhagen, Dept Publ Hlth, DK-1168 Copenhagen, DenmarkUniv London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, England
Andersen, A. F.
Carson, C.
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Univ London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, EnglandUniv London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, England
Carson, C.
Watt, H. C.
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Univ London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, EnglandUniv London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, England
Watt, H. C.
Lawlor, D. A.
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机构:
Univ Bristol, Dept Social Med, Bristol, Avon, EnglandUniv London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, England
Lawlor, D. A.
Avlund, K.
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Univ Copenhagen, Dept Publ Hlth, DK-1168 Copenhagen, DenmarkUniv London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, England
Avlund, K.
Ebrahim, S.
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Univ London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, EnglandUniv London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, England