LIFE COURSE SOCIOECONOMIC POSITION, ALLOSTATIC LOAD, AND INCIDENCE OF TYPE 2 DIABETES AMONG AFRICAN AMERICAN ADULTS: THE JACKSON HEART STUDY, 2000-04 TO 2012

被引:11
|
作者
Beckles, Gloria L. [1 ]
Bullard, Kai McKeever [1 ]
Saydah, Sharon [1 ]
Imperatore, Giuseppina [1 ]
Loustalot, Fleetwood [2 ]
Correa, Adolfo [3 ]
机构
[1] Ctr Dis Control & Prevent, Div Diabet Translat, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
[2] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Atlanta, GA USA
[3] Univ Mississippi, Med Ctr, Jackson, MS 39216 USA
关键词
Life Course Socioeconomic Position; Type; 2; Diabetes; Allostatic Load; African Americans; CHILDHOOD SOCIAL-CLASS; GOAL-STRIVING STRESS; HEALTH; RECALL; MELLITUS; BLACKS; WHITES; GENDER; IMPACT; RISK;
D O I
10.18865/ed.29.1.39
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objective: We examined whether life course socioeconomic position (SEP) was associated with incidence of type 2 diabetes (t2DM) among African Americans. Design: Secondary analysis of data from the Jackson Heart Study, 2000-04 to 2012, using Cox proportional hazard regression to estimate hazard ratios (HR) with 95% CI for t2DM incidence by measures of life course SEP. Participants: Sample of 4,012 nondiabetic adults aged 25-84 years at baseline. Outcome Measure: Incident t2DM identified by self-report, hemoglobin A1c >= 6.5%, fasting plasma glucose >= 126 mg/dL, or use of diabetes medication. Results: During 7.9 years of follow-up, 486 participants developed t2DM (incidence rate 15.2/1000 person-years, 95% CI: 13.9-16.6). Among women, but not men, childhood SEP was inversely associated with t2DM incidence (HR=.97, 95% Cl: .94-.99) but was no longer associated with adjustment for adult SEP or t2DM risk factors. Upward SEP mobility increased the hazard for t2DM incidence (adjusted HR=1.52, 95% CI: 1.05-2.21) among women only. Life course allostatic load (AL) did not explain the SEP-t2DM association in either sex. Conclusions: Childhood SEP and upward social mobility may influence t2DM incidence in African American women but not in men.
引用
收藏
页码:39 / 46
页数:8
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