Schizophrenia: Genome, interrupted

被引:18
|
作者
Cantor, Rita M. [1 ,2 ]
Geschwind, Daniel H. [1 ,2 ,3 ]
机构
[1] Univ Calif Los Angeles, Dept Human Genet, David Geffen Sch Med, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Ctr Neurobehav Genet, Semel Inst, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Program Neurogenet, Dept Neurol, Los Angeles, CA 90095 USA
关键词
D O I
10.1016/j.neuron.2008.04.007
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Structural chromosomal variation is increasingly recognized as an important contributor to human diseases, particularly those of neurodevelopment, such as autism. A current paper makes a significant advance to schizophrenia genetics by establishing an association with rare copy number variants (CNV), which are over-represented in neurodevelopmental genes.
引用
收藏
页码:165 / 167
页数:3
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