Surface Functionalization by Strain-Promoted Alkyne-Azide Click Reactions

被引：83

作者：

Manova, Radostina ^{[1
]}

van Beek, Teris A. ^{[1
]}

Zuilhof, Han ^{[1
]}

机构：

[1] Wageningen Univ, Organ Chem Lab, NL-6703 HB Wageningen, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 24期

关键词：

alkynes; azides; click chemistry; surface chemistry; surface functionalization; CHEMISTRY; IMMOBILIZATION;

D O I：

10.1002/anie.201100835

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Clicks without Cu: There is a growing demand for reproducible site-specific functionalization of surfaces with biomolecules without introduction of unwanted groups or catalysts, as they may interfere with later applications. The title reactions (see picture) could fulfill these requirements, and four recent applications are discussed. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：5428 / 5430

页数：3

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