Anticancer Activities of Medicinal Plants: Modulation of p53 Expression and Induction of Apoptosis

被引：6

作者：

Parveen, Amna ^{[1
,2
]}

Akash, Muhammad Sajid Hamid ^{[2
]}

Rehman, Kanwal ^{[3
]}

Kyunn, Whang Wan ^{[1
]}

机构：

[1] Chung Ang Univ, Dept Pharmacognosy, Coll Pharm, Pharmaceut Resources Bot Lab, Seoul, South Korea

[2] Govt Coll Univ Faisalabad, Dept Pharmaceut Chem, Faisalabad, Pakistan

[3] Univ Agr Faisalabad, Inst Pharm Physiol & Pharmacol, Faisalabad, Pakistan

来源：

CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION | 2016年 / 26卷 / 03期

关键词：

Anticancer properties; apoptosis induction; expression of p53; medicinal plants; CELL-CYCLE ARREST; ANTIPROLIFERATIVE ACTIVITY; ETHANOL EXTRACT; CANCER-CELLS; BCL-2; GENES; CARCINOMA; PROLIFERATION; MECHANISMS; CONSTITUENTS; PROGRESSION;

D O I：

10.1615/CritRevEukaryotGeneExpr.2016016683

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

For the treatment of several types of cancers, tumors and malignancies, scientists are investigating natural sources to discover novel therapeutic agents from medicinal plants having diverse anticancer properties. Research on natural products is being conducted to identify unexplored phytochemical constituents that have been proven to have diverse pharmacological activities. Several medicinal plants have been reported to regulate the progression of different types of cancers, tumors, and malignancies. In this article, we briefly summarize the recent progress in exploring the anticancer properties of various medicinal plants reported to modulate the expression of p53 and the induction of apoptosis. These plants provide a rich source of chemo-protective agents that can ultimately be used to manage cancer progression.

引用

页码：257 / 271

页数：15

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