A New Sesquiterpene from an Endophytic Aspergillus versicolor Strain

被引：0
|
作者：
Liu, Xiang-Hong [1 ]
Miao, Feng-Ping [1 ]
Li, Xiao-Dong [1 ]
Yin, Xiu-Li [1 ]
Ji, Nai-Yun [1 ]
机构：
[1] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
来源：
NATURAL PRODUCT COMMUNICATIONS | 2012年 / 7卷 / 07期
关键词：
Sesquiterpene; Albican-11,14-diol; Aspergillus versicolor; Codium fragile; SECONDARY METABOLITES; SPECTRA;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new sesquiterpene, albican-11,14-diol (1), and seven known compounds, including sterigmatocystin (2), 3-hydroxy-5-(hydroxymethyl)-4-(4'-hydroxyphenoxy) pyrrolidin-2-one (3), (1H-indol-3-yl) oxoacetamide (4), indole-3-carboxylic acid (5), indole-3-acetic acid (6), indole-3-carboxaldehyde (7), and volemolide (8), were isolated from the cultures of Aspergillus versicolor, an endophytic fungus isolated from the marine green alga Codium fragile. The structure of 1 was elucidated by 1D, 2D NMR and mass spectroscopic techniques. The bioassay results showed that 1 possessed potent activity against brine shrimp, Escherichia colt, and Staphyloccocus aureus.
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页码：819 / 820
页数：2
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