A new class of tight binding non-nucleoside reverse transcriptase inhibitors inhibit the burst and steady-state phases of wild-type and Y188L HIV-1 reverse transcriptase activity

被引：0
|
作者：
Leveque, V. [1 ]
Giannetti, Tony [1 ]
Li, Y. [1 ]
Deval, J. [1 ]
Harris, S. [1 ]
Cammack, N. [1 ]
Klumpp, K. [1 ]
机构：
[1] Roche Palo Alto LLC, Palo Alto, CA 94304 USA
来源：
ANTIVIRAL THERAPY | 2008年 / 13卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
引用
收藏
页码：A58 / A58
页数：1
相关论文
共 50 条
  • [1] Non-nucleoside inhibitors of HIV-1 reverse transcriptase
    Proudfoot, JR
    EXPERT OPINION ON THERAPEUTIC PATENTS, 1998, 8 (08) : 971 - 982
  • [2] HIV-1 non-nucleoside reverse transcriptase inhibitors
    Högberg, M
    Morrison, I
    EXPERT OPINION ON THERAPEUTIC PATENTS, 2000, 10 (08) : 1189 - 1199
  • [3] Effect of non-nucleoside reverse transcriptase inhibitors on the HIV-1 reverse transcriptase associated ribonuclease H activity
    Tramontano, E
    Esposito, F
    Piras, A
    La Colla, P
    ANTIVIRAL RESEARCH, 2005, 65 (03) : A51 - A51
  • [4] QSAR for non-nucleoside inhibitors of HIV-1 reverse transcriptase
    Duchowicz, Pablo R.
    Fernandez, Michael
    Caballero, Julio
    Castro, Eduardo A.
    Fernandez, Francisco M.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (17) : 5876 - 5889
  • [5] Hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in HIV-1
    Moreno, S
    Casado, JL
    Pérez-Elias, MI
    Dronda, F
    Antela, A
    Moreno, A
    Gutiérrez, C
    AIDS, 2003, 17 (09) : 1413 - 1414
  • [6] Non-nucleoside inhibitors of HIV-1 reverse transcriptase binding calculations.
    Zhou, ZG
    Madrid, M
    Madura, JD
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 222 : U397 - U397
  • [7] NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities
    Thammaporn, Ratsupa
    Yagi-Utsumi, Maho
    Yamaguchi, Takumi
    Boonsri, Pornthip
    Saparpakorn, Patchreenart
    Choowongkomon, Kiattawee
    Techasakul, Supanna
    Kato, Koichi
    Hannongbua, Supa
    SCIENTIFIC REPORTS, 2015, 5
  • [8] NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities
    Ratsupa Thammaporn
    Maho Yagi-Utsumi
    Takumi Yamaguchi
    Pornthip Boonsri
    Patchreenart Saparpakorn
    Kiattawee Choowongkomon
    Supanna Techasakul
    Koichi Kato
    Supa Hannongbua
    Scientific Reports, 5
  • [9] Mass Spectrometric Characterization of HIV-1 Reverse Transcriptase Interactions with Non-nucleoside Reverse Transcriptase Inhibitors
    Thammaporn, Ratsupa
    Ishii, Kentaro
    Yagi-Utsumi, Maho
    Uchiyama, Susumu
    Hannongbua, Supa
    Kato, Koichi
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2016, 39 (03) : 450 - 454
  • [10] A new insertion in the HIV-1 reverse transcriptase gene inducing major resistance to non-nucleoside reverse transcriptase inhibitors
    Amiel, C
    Desire, N
    Schneider, V
    Delphin, N
    Race, E
    Clavel, F
    Piolot, T
    Dam, E
    Rozenbaum, W
    Nicolas, JC
    AIDS, 2005, 19 (16) : 1922 - 1924
12345