Medial temporal-lobe damage and memory for emotionally arousing odors

被引:28
|
作者
Pouliot, Sandra [1 ]
Jones-Gotman, Marilyn [1 ]
机构
[1] McGill Univ, Montreal Neurol Inst, Montreal, PQ H3A 2B4, Canada
基金
加拿大健康研究院;
关键词
amygdala; hippocampus; arousal; pleasantness;
D O I
10.1016/j.neuropsychologia.2007.10.017
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Recently, we found that healthy young adults remember odors leading to large emotional reactions better than odors provoking smaller emotional reactions. Because the amygdala is believed to be critically implicated in memory for emotionally arousing information and because it is part of the primary olfactory area, we hypothesized that patients with a unilateral medial temporal-lobe resection including the amygdala would not show enhanced memory for arousing compared to nonarousing odors. We tested odor memory in 19 patients (10 left, 9 right) who had undergone a unilateral medial temporal-lobe resection including the amygdala (MTLR) for treatment of intractable epilepsy and 19 healthy control subjects. Healthy individuals and patients with left or right MTLR showed comparable subjective emotional reactions to odors. Similarly, healthy individuals and patients with MTLR remembered unpleasant odors better than pleasant ones. However, unlike healthy individuals, patients with MTLR did not show better memory for emotionally arousing odors compared to nonarousing ones. Patients undergoing a MTLR, whether in the left or right hemisphere, lose the specific memory advantage that odors causing strong emotional reactions normally have. (c) 2007 Elsevier Ltd. All rights reserved.
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页码:1124 / 1134
页数:11
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