Nematode Infections: Filariases

被引：14

作者：

Knopp, Stefanie ^{[1
,2
]}

Steinmann, Peter ^{[1
,2
]}

Hatz, Christoph ^{[1
,3
,5
]}

Keiser, Jennifer ^{[1
,4
]}

Utzinger, Juerg ^{[1
,2
]}

机构：

[1] Univ Basel, CH-4003 Basel, Switzerland

[2] Swiss Trop & Publ Hlth Inst, Dept Epidemiol & Publ Hlth, CH-4002 Basel, Switzerland

[3] Swiss Trop & Publ Hlth Inst, Dept Med Serv & Diagnost, CH-4002 Basel, Switzerland

[4] Swiss Trop & Publ Hlth Inst, Dept Med Parasitol & Infect Biol, CH-4002 Basel, Switzerland

[5] Univ Zurich, Inst Social & Prevent Med, CH-8001 Zurich, Switzerland

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2012年 / 26卷 / 02期

基金：

比尔及梅琳达.盖茨基金会;

关键词：

Filariasis; Dracunculus medinensis; Loa loa; Mansonella perstans; Onchocerca volvulus; Wuchereria bancrofti; Epidemiology; Control; GUINEA WORM DISEASE; LYMPHATIC FILARIASIS; DOUBLE-BLIND; WUCHERERIA-BANCROFTI; GLOBAL PROGRAM; LOA-LOA; DOXYCYCLINE TREATMENT; DONATION PROGRAM; HUMAN LOIASIS; END-POINTS;

D O I：

10.1016/j.idc.2012.02.005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

More than 150 million people, mainly in developing countries, are affected by filarial nematode infections that cause debilitating and disfiguring diseases. Although transmission is restricted to the tropics and subtropics, imported infections sometimes occur in Europe and North America among immigrants and refugees from endemic countries, and rarely among long-term travelers. This article reviews the epidemiology of the most important human filarial nematodes, their current distribution, life cycles, clinical features, and disease burden. Diagnosis, treatment, and tools for prevention and control are discussed. Protective measures for travelers are summarized, and vulnerable groups and case numbers in North America identified.

引用

页码：359 / +

页数：25

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