Long-term neurodevelopmental outcomes among preterm infants born to mothers with diabetes mellitus

被引:1
|
作者
Sugar, Jenna [1 ,2 ]
Lum, Trenton G. [1 ,2 ]
Fertel, Sophie [1 ]
Yim, Rachel [1 ]
Morales, Ana
Poeltler, Debra [1 ]
Katheria, Anup [1 ]
机构
[1] Sharp Mary Birch Hosp Women & Newborns, Neonatal Res Inst, 3003 Hlth Ctr Dr, San Diego, CA 92123 USA
[2] Western Univ Hlth Sci, Coll Osteopath Med Pacif, 615 3rd St, Pomona, CA 91766 USA
关键词
HYPERGLYCEMIA; AGE;
D O I
10.1038/s41372-021-01255-8
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Background The long-term effects of maternal diabetes on preterm infant neurodevelopment are unknown. This study aims to determine if there was an increased likelihood of neurodevelopmental impairment in preterm infants born to mothers with diabetes. Materials and methods A retrospective cohort study was conducted on preterm infants with neurodevelopmental evaluations at 18-36 months corrected age using the Bayley Scales of Infant and Toddler Development Third edition. Results 680 former preterm infants were evaluated. There was no difference in cognitive, language, and motor scores. Infants born to diabetic mothers with AMA were significantly different in cognitive (adjusted-beta (a-beta),-7.24 [95%CI, -11.719 to -2.769]; P = 0.002) and language domains (a-beta,-7.783 [95%CI, -13.603 to -1.963]; (P = 0.009). Discussion There was no significant difference in neurodevelopmental outcomes of preterm infants exposed to maternal diabetes. Preterm infants born to mothers with diabetes and AMA demonstrated lower cognitive and language scores at 2 years corrected age.
引用
收藏
页码:499 / 502
页数:4
相关论文
共 50 条
  • [1] Long-term neurodevelopmental outcomes among preterm infants born to mothers with diabetes mellitus
    Jenna Sugar
    Trenton G. Lum
    Sophie Fertel
    Rachel Yim
    Ana Morales
    Debra Poeltler
    Anup Katheria
    [J]. Journal of Perinatology, 2022, 42 : 499 - 502
  • [2] LONG-TERM NEURODEVELOPMENTAL OUTCOMES AMONG PRETERM INFANTS EXPOSED TO GESTATIONAL DIABETES MELLITUS
    Sugar, J.
    Lum, T.
    Poeltler, D.
    Katheria, A.
    [J]. JOURNAL OF INVESTIGATIVE MEDICINE, 2020, 68 : A23 - A23
  • [3] Extremely preterm born infants and long-term neurodevelopmental outcomes
    Briana, Despina D.
    Malamitsi-Puchner, Ariadne
    [J]. ACTA PAEDIATRICA, 2020, 109 (07) : 1499 - 1499
  • [4] Long-term neurodevelopmental outcomes of infants born late preterm: a systematic review
    Tripathi, Tanya
    Dusing, Stacey C.
    [J]. RESEARCH AND REPORTS IN NEONATOLOGY, 2015, 5 : 91 - 111
  • [5] FEEDING PROBLEMS IN IN LATE PRETERM AND TERM INFANTS BORN TO MOTHERS WITH DIABETES MELLITUS
    Peravali, S.
    Chilakala, S. K.
    Talati, A. J.
    [J]. JOURNAL OF INVESTIGATIVE MEDICINE, 2019, 67 (02) : 527 - 527
  • [6] Predictors of long-term neurodevelopmental outcomes of children born extremely preterm
    Spittle, Alicia J.
    Thompson, Deanne K.
    Olsen, Joy E.
    Kwong, Amanda
    Treyvaud, Karli
    [J]. SEMINARS IN PERINATOLOGY, 2021, 45 (08)
  • [7] Long-Term Neurodevelopmental and Functional Outcomes of Infants Born Very Preterm and/or with a Very Low Birth Weight
    Hollanders, Jonneke J.
    Schaefer, Nina
    van der Pal, Sylvia M.
    Oosterlaan, Jaap
    Rotteveel, Joost
    Finken, Martijn J. J.
    Hille, E. T. M.
    de Groot, C. H.
    Kloosterboer-Boerrigter, H.
    den Ouden, A. L.
    Rijpstra, A.
    Verloove-Vanhorick, S. P.
    Vogelaar, J. A.
    Kok, J. H.
    Ilsen, A.
    van der Lans, M.
    Boelen-van der Loo, W. J. C.
    Lundqvist, T.
    Heymans, H. S. A.
    Duiverman, E. J.
    Geven, W. B.
    Duiverman, M. L.
    Geven, L. I.
    Vrijlandt, E. J. L. E.
    Mulder, A. L. M.
    Gerver, A.
    Kollee, L. A. A.
    Reijmers, L.
    Sonnemans, R.
    Wit, J. M.
    Dekker, F. W.
    Weisglas-Kuperus, N.
    Keijzer-Veen, M. G.
    van der Heijden, A. J.
    van Goudoever, J. B.
    van Weissenbruch, M. M.
    Cranendonk, A.
    Delemarre-van de Waal, H. A.
    de Groot, L.
    Samsom, J. F.
    de Vries, L. S.
    Rademaker, K. J.
    Moerman, E.
    Voogsgeerd, M.
    de Kleine, M. J. K.
    Andriessen, P.
    Dielissen-van Helvoirt, C. C. M.
    Mohamed, I.
    van Straaten, H. L. M.
    Baerts, W.
    [J]. NEONATOLOGY, 2019, 115 (04) : 310 - 319
  • [8] WHAT ARE THE FACTORS INFLUENCING LONG-TERM OUTCOMES FOR INFANTS BORN PRETERM?
    Leonard, H.
    Bourke, J.
    Wong, K.
    Srinivasjois, R.
    Pereira, G.
    Shepherd, C.
    White, S.
    Stanley, F.
    [J]. JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2019, 63 (07) : 790 - 791
  • [9] Long-term cognitive outcomes of infants born moderately and late preterm
    Odd, David Edward
    Emond, Alan
    Whitelaw, Andrew
    [J]. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2012, 54 (08): : 704 - 709
  • [10] LONG-TERM OUTCOME OF INFANTS BORN PRETERM
    KNOCHES, AML
    DOYLE, LW
    [J]. BAILLIERES CLINICAL OBSTETRICS AND GYNAECOLOGY, 1993, 7 (03): : 633 - 651