Non-invasive prenatal diagnosis and determination of fetal Rh status

被引：60

作者：

van der Schoot, C. Ellen ^{[1
,2
]}

Hahn, Sinuhe ^{[3
]}

Chitty, Lyn S. ^{[4
,5
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Landsteiner Lab, NL-1066 CX Amsterdam, Netherlands

[2] Sanquin Res, Amsterdam, Netherlands

[3] Univ Basel Hosp, Univ Womens Hosp, Dept Res, Basel, Switzerland

[4] UCL Hosp, NHS Fdn Trust, Fetal Med Unit, London, England

[5] UCL Hosp, NHS Fdn Trust, Clin & Mol Genet Unit, Inst Child Hlth, London, England

来源：

SEMINARS IN FETAL & NEONATAL MEDICINE | 2008年 / 13卷 / 02期

关键词：

fetal RHD status; non-invasive prenatal; diagnosis; cell-free fetal DNA;

D O I：

10.1016/j.siny.2007.12.012

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

RhD blood group incompatibility between a pregnant woman and her fetus can result in maternal alloimmunization and consequent haemolytic disease of the newborn (HDN) in subsequent pregnancies. The D-negative blood group is found in 15% of whites, 3-5% of black Africans, and is rare in Asians. Recent technological advances in non-invasive prenatal determination of the fetal RHD status using cell-free fetal DNA (cffDNA) have opened new avenues for the management of D-negative pregnant women. In this review applications for the high risk women, as well as potential for routine screening wilt be discussed. The use of non-invasive prenatal diagnosis and the management of other blood incompatibilities wilt also be discussed. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：63 / 68

页数：6

共 50 条

[41] Recent progress in non-invasive prenatal diagnosis
Hahn, Sinuhe
Zhong, Xiao Yan
Holzgreve, Wolfgang
SEMINARS IN FETAL & NEONATAL MEDICINE, 2008, 13 (02): : 57 - 62
[42] Non-invasive prenatal diagnosis: The patient perspective
Lewis, Celine
JOURNAL OF MEDICAL GENETICS, 2011, 48 : S23 - S23
[43] Non-invasive prenatal diagnosis: an ethical imperative
Vardit Ravitsky
Nature Reviews Genetics, 2009, 10 : 733 - 733
[44] Non-invasive prenatal diagnosis: an ethical imperative
Ravitsky, Vardit
NATURE REVIEWS GENETICS, 2009, 10 (10) : 733 - 733
[45] Chapter 2: Non-invasive prenatal diagnosis
Allen, Stephanie K.
Doyleb, Samantha
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY, 2024, 97
[46] Non-invasive prenatal diagnosis of cystic fibrosis
Brechot, P. Paterlini
Mouawia, H.
Saker, A.
ARCHIVES DE PEDIATRIE, 2011, 18 (01): : 111 - 118
[47] Non-invasive prenatal diagnosis: progress and potential
Daley, Rebecca
Hill, Melissa
Chitty, Lyn S.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2014, 99 (05): : E426 - E430
[48] Non-invasive prenatal diagnosis: new challenges
Benn, Peter
CHROMOSOME RESEARCH, 2011, 19 : S22 - S22
[49] New trend in non-invasive prenatal diagnosis
Ferrari, M.
Carrera, P.
Lampasona, V.
Galbiati, S.
CLINICA CHIMICA ACTA, 2015, 451 : 9 - 13
[50] Non-invasive prenatal diagnosis for HbSC disease
Gerovassili, A.
Clark, B. E.
Colella, S.
Nicolaides, K. H.
Ragoussis, J.
Thein, S. L.
Rees, D. C.
BRITISH JOURNAL OF HAEMATOLOGY, 2007, 137 : 87 - 87

← 1 2 3 4 5 →